1038081-85-4Relevant academic research and scientific papers
Synthesis of (Z)-2-(4-substitutedbenzylidene)-7-isocyano-3,6-dioxo-8- phenyl-3,6-dihydro-2H-thiazolo-[3′,2′:2,3][1,2,4] triazolo[1,5-a]pyridine-9-carbonitrile
Suresh, Maddila,Jonnalagadda, Sreekanth B.,Rao, Chunduri Venkata
scheme or table, p. 127 - 133 (2012/01/06)
A series of (Z)-2-(4-substitutedbenzylidene)-7-isocyano-3,6-dioxo-8-phenyl- 3,6-dihydro-2H-thiazolo-[3′,2′:2,3][1,2,4]triazolo[1,5-a] pyridine-9-carbonitrile derivatives (4a-j) were obtained by the initial reaction of 5-oxo-7-phenyl-2-thiol-3,5-dihydro[1,2,4]-triazolo[1,5-a]pyridine-6,8- dicarbonitrile (3) with chloroacetic acid and appropriate aromatic aldehydes followed by fused sodium acetate condensation. The structures of the newly synthesized compounds were confirmed by IR,1H NMR, Mass and analytical data. Compounds 4a, 4f, 4i and 4j exhibited good antimicrobial activity.
Fused pyridines by a tandem aza-Wittig / heterocyclization strategy: Synthesis of 1,2,4-triazolo[1,5-a]pyridines and pyrido[1,2-b][1,2,4]triazines
Barsy, Magda A.,El Rady, Eman A.,Abd El Latif, Fawi M.
, p. 773 - 778 (2008/09/21)
(Chemical Equation Presented) The iminophosphorane 1-amino-6- (triphenylphosphoranylideneamino)-2-oxo-4-phenyl-1,2-dihydropyridine-3, 5-dicarbonitrile 2 prepared from 1,6-diaminopyridine 1 reacts with heterocumulenes such as carbon disulfide and phenylisocyanate, and with acid chlorides, acid anhydrides and haloketones to give directly the title compounds in an one-pot aza-Wittig / heterocyclic-ring closure process with good yields.
