1038434-07-9Relevant academic research and scientific papers
Copper-catalyzed intermolecular generation of ammonium ylides with subsequent [2,3]sigmatropic rearrangement. Efficient synthesis of bifunctional homoallylamines
Honda, Kiyoshi,Shibuya, Hiromasa,Yasui, Hiroto,Hoshino, Yujiro,Inoue, Seiichi
, p. 142 - 147 (2008)
The [2,3]sigmatropie rearrangement of allylic ammonium ylides generated by the reaction of N,N-dimethyl-l- alkyl-2-methylallylamines derived from terpene alcohols with diazo compounds in the presence of copper catalysts gave trisubstituted E-olefins in one-pot. In addition, a cyano substituent at the 2-position of N,N-dimethylallylamine increased the occurrence of the catalytic [2,3]sigmatropic rearrangement to give the corresponding bifunctional homoallylamines. 2008 The Chemical Society of Japan.
