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1H-Indene-4-carboxylic acid, 7-(acetyloxy)-1-[(1R,3S,4E)-5-carboxy-3-hydroxy-1-methyl-4-hexen-1-yl]-5-[[(1S,4S)-3,3-dimethyl-2-oxo-7-oxabicyclo[2.2.1]hept-1-yl]methyl]-2,6,7,7a-tetrahydro-1,7a-dimethyl-,(1S,7R,7aR)-, commonly known as acitretin, is a synthetic retinoid with anti-psoriatic and antineoplastic properties. It is characterized by its complex molecular structure, which allows it to target specific receptors in the skin and regulate gene expression to inhibit the proliferation of abnormal skin cells.

103847-17-2

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103847-17-2 Usage

Uses

Used in Pharmaceutical Industry:
Acitretin is used as an anti-psoriatic agent for the treatment of severe psoriasis and other skin disorders. It works by regulating the growth of skin cells and targeting specific receptors in the skin to alter gene expression, thereby inhibiting the proliferation of abnormal skin cells.
Used in Oncology:
Acitretin is also used as an antineoplastic agent in the treatment of certain types of cancer. Its anti-psoriatic properties can be beneficial in managing skin-related symptoms associated with cancer and its treatment.
Used in Long-term Treatment:
Due to its effectiveness in treating severe skin conditions, acitretin is usually prescribed for long-term use. However, it is important to note that it can cause serious side effects and is not recommended for use in pregnant women due to its potential to cause birth defects.

Check Digit Verification of cas no

The CAS Registry Mumber 103847-17-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,3,8,4 and 7 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 103847-17:
(8*1)+(7*0)+(6*3)+(5*8)+(4*4)+(3*7)+(2*1)+(1*7)=112
112 % 10 = 2
So 103847-17-2 is a valid CAS Registry Number.

103847-17-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name glycinoeclepin B

1.2 Other means of identification

Product number -
Other names (1S,7aS)-7-Acetoxy-1-((E)-(1R,3S)-5-carboxy-3-hydroxy-1-methyl-hex-4-enyl)-5-((1S,4S)-3,3-dimethyl-2-oxo-7-oxa-bicyclo[2.2.1]hept-1-ylmethyl)-1,7a-dimethyl-2,6,7,7a-tetrahydro-1H-indene-4-carboxylic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:103847-17-2 SDS

103847-17-2Upstream product

103847-17-2Downstream Products

103847-17-2Relevant academic research and scientific papers

GLYCINOECLEPINS B AND C, NORTRITERPENES RELATED TO GLYCINOECLEPIN A

Fukuzawa, Akio,Matsue, Hideki,Ikura, Mitsuhiko,Masamune, Tadashi

, p. 5539 - 5542 (1985)

The structure of two new nortriterpenes, glycinoeclepins B and C, isolated from the aqueous extracts of roots of kidney bean and related structurally to glycinoeclepin A, a natural hatching stimulus for the soybean cyst nematode, has been elucidated to be formulas 2 and 3, respectively.

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