103860-60-2Relevant academic research and scientific papers
Self-assembly of non-macrocyclic triangular Ni3Ln clusters
Dais, Tyson N.,Ishida, Takayuki,Plieger, Paul G.,Takano, Rina
, p. 1446 - 1453 (2022/02/03)
The synthesis and structural characterisation of four new heterometallic tetranuclear complexes is reported. Three L3Ni3Ln type complexes, where Ln = La (C1), Eu (C2), and Gd (C3), have been fully characterised including DC and AC magnetic measurements. A fourth complex featuring a diamagnetic BaII ion at its centre is also reported with structural characterisation. Structural elucidation showed that all four complexes successfully self-assembled from a stoichiometric mixture of the acyclic ligand, 1,4-diformylnaphthalene-2,3-diol, with nickel(ii) nitrate and the appropriate heavy metal salt to produce the same near planar Ni3MO12 core. Ferromagnetic interactions were found to dominate the ground state of C3, exhibiting a maximal spin ground state of 13/2. The exchange coupling is quantitatively discussed along with the nickel(ii) zero-field splitting effect. AC magnetic susceptibility experiments were carried out, but no frequency dependent signals were observed and thus no observable slow relaxation of magnetisation.
Novel lysosome-targeted fluorescent molecular rotors based on a cyanine-like modular system and their application in living cells
Cai, Yiping,Liu, Chang,Lei, Zhaoxia,Wang, Zhiming,Bian, Yaye,He, Song,Zeng, Xianshun
, (2021/09/28)
Two novel fluorescence molecular rotors DpIn and NaIn were designed and synthesized involving of indolium units linked with meta-diphenol or ortha-naphthalenediol moiety, respectively. They underwent intramolecular charge transfer to form a cyanine-like modular system at a physiological pH. In glycerol aqueous solutions, the probe DpIn exhibited NIR strong emission (3-fold) at ca. 700 nm, while the probe NaIn displayed a turn-on emission (8-fold) with a larger Stokes shift (⊿λ ≈ 97 nm). The HeLa cell imaging experiments indicated probe DpIn and NaIn both exhibited excellent selectivity for staining intracellular lysosomes instead of mitochondria. 1H NMR spectra revealed that more electrons were accumulated around benzene ring of indolium groups, which could be the evidence for its basic character leading to the lysosomes targeted staining. Furthermore, the probe NaIn proved to be an ideal lysosome-targeting tracer for monitor the changes of viscosity caused by stimuli in living cells.
Structure-Activity Relationship Studies of Coumarin-like Diacid Derivatives as Human G Protein-Coupled Receptor-35 (hGPR35) Agonists and a Consequent New Design Principle
Wei, Lai,Hou, Tao,Li, Jiaqi,Zhang, Xiuli,Zhou, Han,Wang, Zhenyu,Cheng, Junxiang,Xiang, Kaijing,Wang, Jixia,Zhao, Yaopeng,Liang, Xinmiao
supporting information, p. 2634 - 2647 (2021/04/02)
A series of coumarin-like diacid derivatives were designed and synthesized as novel agonists of human G-protein-coupled receptor 35 (hGPR35). Active compounds were characterized to possess one acidic group on both sides of a fused tricyclic aromatic scaff
Synthesis and fluorescence properties of a new heterotrinuclear Co(II)-Ce(III)Complex constructed from a bis(salamo)-type tetraoxime ligand
Pu, Lu-Mei,Zhao, Qing,Liu, Ling-Zhi,Zhang, Han,Long, Hai-Tao,Dong, Wen-Kui
, (2018/04/09)
[Co2(L)Ce(OAc)3(CH3CH2OH)]·1.5CH3OH·0.5CH2Cl2, a heterotrinuclear Co(II)-Ce(III) bis(salamo)-type complex with a symmetric bi(salamo)-type ligand H4L and an acyclic naphthalenediol moiety, was designed, synthesized and characterized by elemental analyses, FT-IR, UV-Vis and fluorescence spectroscopy and X-ray crystallography. The X-ray crystallographic investigation revealed the heterotrinuclear complex consisted of two Co(II) atoms, one Ce(III) atom, one (L)4- unit, three μ2-acetate ions, one coordinated ethanol molecule, one and half crystallization methanol molecule and half crystallization dichloromethane molecule. Two Co(II) atoms located in the N2O2 coordination spheres, are both hexacoordinated, with slightly distorted octahedral geometries. The Ce(III) atom is nine-coordinated and located in the O6 cavity possesses a single square antiprismatic geometry. In addition, supramolecular interactions exist in the Co(II)-Ce(III) complex. Two infinite 2D supramolecular structures are built via intermolecular O–H···O, C–H···O and C–H···π interactions, respectively.
Self-assembly properties of Salamo-type trinuclear Cu(II) and Co(II) complexes based on the regulation of H+/OHˉ
Dong, Xiu-Yan,Wang, Bao-Jun,Kang, Quan-Peng,Dong, Wen-Kui
, (2018/04/30)
A novel naphthalenediol-based bis(salamo)-type tetraoxime compound (H4L) was designed and synthesized. Two new supramolecular complexes, [Cu3(L)(μ-OAc)2] and [Co3(L)(μ-OAc)2(MeOH)2]·4CHCl3 were synthesized by the reaction of H4L with Cu(II) acetate dihydrate and Co(II) acetate dihydrate, respectively, and were characterized by elemental analyses and X-ray crystallography. In the Cu(II) complex, Cu1 and Cu2 atoms located in the N2O2 sites, and are both penta-coordinated, and Cu3 atom is also penta-coordinated by five oxygen atoms. All the three Cu(II) atoms have geometries of slightly distorted tetragonal pyramid. In the Co(II) complex, Co1 and Co3 atoms located in the N2O2 sites, and are both penta-coordinated with geometries of slightly distorted triangular bipyramid and distorted tetragonal pyramid, respectively, while Co2 atom is hexa-coordinated by six oxygen atoms with a geometry of slightly distorted octahedron. These self-assembling complexes form different dimensional supramolecular structures through inter- and intra-molecular hydrogen bonds. The coordination bond cleavages of the two complexes have occurred upon the addition of the H+, and have reformed again via the neutralization effect of the OH?. The changes of the two complexes response to the H+/OH? have observed in the UV–Vis and 1H NMR spectra.
Naphthalenediol-based bis(Salamo)-type homo- and heterotrinuclear cobalt(II) complexes: Syntheses, structures and magnetic properties
Zhang, Han,Dong, Wen-Kui,Zhang, Yang,Folaranmi Akogun, Sunday
, p. 279 - 293 (2017/06/19)
Homo- and heterotrinuclear Co(II) complexes with a new acyclic bis(Salamo)-type ligand H4L, which bears a C-shaped O6 site by the metallation of the N2O2 Salamo moieties, were synthesized. The homotrinuclear complex [Co3(L)(OAc)2(CH3OH)2]·2CHCl3 (1) was obtained by the reaction of H4L with 3 equivalents of Co(OAc)2·4H2O. The heterotrinuclear complexes [Co2(L)Ca(OAc)2] (2), [Co2(L)Sr(OAc)2] (3) and [Co2(L)Ba(OAc)2(H2O)]·2CH3CH2OH (4) were acquired by the reaction of H4L with 2 equivalents of Co(OAc)2·4H2O and 1 equivalent of M(OAc)2 (M?=?Ca(II), Sr(II) and Ba(II)). In the crystal structures, the three metal(II) atoms occupy both the N2O2 and O6 sites of the ligand (L)4? moiety. Owing to the different nature of the N2O2 and O6 sites of the ligand H4L, the introduction of two different metal(II) atoms to the site-selective moiety, when compared with complex 1, leads to the replacement of the central Co(II) atom by different alkaline earth metal(II) atoms, namely the Ca(II), Sr(II) and Ba(II) atoms for complexes 2, 3 and 4, respectively. Magnetic measurements were performed on complexes 1–4, where an intramolecular ferromagnetic interaction was found in complex 3 and intramolecular antiferromagnetic interactions were found in complexes 1, 2 and 4. The magnetic susceptibilities above 50?K obey the Curie–Weiss law and their constant values were determined for all the complexes.
Four homo- and hetero-bismetallic 3d/3d-2s complexes constructed from a naphthalenediol-based acyclic bis(salamo)-type tetraoxime ligand
Hao, Jing,Li, Li-Long,Zhang, Jin-Tong,Akogun, Sunday Folaranmi,Wang, Li,Dong, Wen-Kui
, p. 1 - 10 (2017/06/27)
The homo/heterotrinuclear metal(II) complexes [Zn3(L)(OAc)2(CH3OH)2]·3CHCl3 (1), [Zn2(L)Ca(OAc)2]·CHCl3 (2), [Zn2(L)Sr(OAc)2] (3) and [Zn2Ba(L)(OAc)2(CH3OH)]·CH3OH·CHCl3 (4), with a novel acyclic bis(salamo)-type tetraoxime ligand H4L, were synthesized and characterized by elemental analyses, IR, UV–vis and fluorescence spectra. UV–vis titrations clearly show that complexation of H4L with Zn(II) ions affords a stoichiometric ratio of 3:1 (M:L) in a cooperative fashion. Complexes 2, 3 and 4 can acquire by the substitution reactions of complex 1 with 1 equivalent of M(OAc)2 (M2+?=?Ca2+, Sr2+ or Ba2+). The crystal structures of complexes 1–4 have been determined by single-crystal X-ray diffraction. The coordinating ability of the [Zn3(L)]2+ units may be utilized as a cation recognition phenomenon.
Syntheses, structures and catecholase activities of homo- and hetero-trinuclear cobalt(II) complexes constructed from an acyclic naphthalenediol-based bis(Salamo)-type ligand
Li, Li-Hong,Dong, Wen-Kui,Zhang, Yang,Akogun, Sunday Folaranmi,Xu, Li
, (2017/09/30)
A series of homo- and hetero-trinuclear cobalt(II) complexes [Co3(L)(OAc)2(CH3CH2OH)(H2O)] (1), [Co2Ba(L)(OAc)2] (2) and [Co2Ca(L)(OAc)2]·CHCl3 (
Formylation of phenols using formamidine acetate
Mehr, S. Hessam M.,Depmeier, Hannah,Fukuyama, Katsuya,Maghami, Mahboobeh,MacLachlan, Mark J.
supporting information, p. 581 - 583 (2017/01/25)
We report a new method to formylate phenol derivatives using formamidine acetate and acetic anhydride. This general-purpose transformation is a significant improvement over many other methods and does not require high temperatures or the addition of strong acid or base. Mono-, di-, and tri-formylated product can be obtained, depending on the substrate and conditions used.
Synthesis of "calixarene-like" N,N-ditosyldiaza[3.3](1,4) naphthalenophanes
Tran, Huu-Anh,Collins, Julie,Georghiou, Paris E.
experimental part, p. 1175 - 1182 (2009/02/02)
A series of new tetrahomodiazacalix[2]naphthalenes, containing 2,3-dialkoxy-substituted naphthalene units, have been synthesized and some of their properties are reported. All of the newly-synthesized macrocycles were highly symmetrical and conformational
