1038863-74-9Relevant academic research and scientific papers
An enantioselective approach to (+)-laurencin
Adsool, Vikrant A.,Pansare, Sunil V.
, p. 2011 - 2015 (2008)
A convergent enantioselective route to an advanced intermediate for the synthesis of the marine natural product (+)-laurencin has been developed. The methodology employs ring-opening of an ephedrine-based spiro-epoxide with a chiral secondary alcohol, hemiacetal allylation and ring closing metathesis as the key steps for elaboration of the functionalized medium-ring ether moiety in laurencin. The Royal Society of Chemistry.
