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Product FOB Price Min.Order Supply Ability Supplier
Cas No: 1038915-60-4
No Data No Data Metric Ton/Day Beijing Mesochem Technology Co.,LTD Contact Supplier
Niraparib 100kgs in stock factory
Cas No: 1038915-60-4
USD $ 150.0-150.0 / Gram 1 Gram 1000 Gram/Day Shenzhen Tianyuan Pharmaceutical Technology Co., Ltd Contact Supplier
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No Data 10 Gram Metric Ton/Day Shanghai Biobond Pharmaceutical Co.,Ltd Contact Supplier
Cas No: 1038915-60-4
USD $ 3.0-3.0 / Kilogram 1 Kilogram 1-100 Metric Ton/Month Hangzhou Dayangchem Co., Ltd. Contact Supplier
best quality 1038915-60-4 Niraparib Wholesaler
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No Data 10 Metric Ton Metric Ton/Day Amadis Chemical Co., Ltd. Contact Supplier
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No Data No Data No Data Chemwill Asia Co., Ltd. Contact Supplier
1038915-60-4 C19H20N4O (S)-2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-carboxamide
Cas No: 1038915-60-4
No Data 100 Gram 1 Kilogram/Day HENAN SUNLAKE ENTERPRISE CORPORATION Contact Supplier
Factory supply Niraparib cas 1038915-60-4 with best price
Cas No: 1038915-60-4
No Data No Data 1000 Metric Ton/Month Crovell Biotech (Hebei) Co., Ltd. Contact Supplier
high quality 1038915-60-4 Niraparib with best price
Cas No: 1038915-60-4
No Data 10 Gram 1000 Metric Ton/Month Hubei XinRunde Chemical Co., Ltd Contact Supplier
Niraparib 1038915-60-4
Cas No: 1038915-60-4
USD $ 500.0-500.0 / Metric Ton 1 Metric Ton 1 Metric Ton/Day Henan Tianfu Chemical Co., Ltd. Contact Supplier

1038915-60-4 Usage


Sandhu, Shahneen K, et al. "The poly (ADP-ribose) polymerase inhibitor niraparib (MK4827) in BRCA, mutation carriers and patients with sporadic cancer: a phase 1 dose-escalation trial." Lancet Oncology14.9 (2013):882.
Jones, P, et al. "Niraparib: A Poly (ADP-ribose) Polymerase (PARP) Inhibitor for the Treatment of Tumors with Defective Homologous Recombination. " Journal of Medicinal Chemistry 58.8(2015):3302-14.


(S)-2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-carboxamide is also known as MK-4827(Niraparib) tosylate is a selective inhibitor of PARP1/PARP2 (The poly(ADP-ribose) polymerase) with great activity in cancer cells with mutant BRCA-1 and BRCA-2. It has been recently approved by FDA for the maintenance treatment of adult patients with recurrent epithelial ovarian, fallopian tube, or primary peritoneal cancer who are in complete or partial response to platinum-based chemotherapy. In vitro studies have shown that niraparib-induced cytotoxicity may involve inhibition of PARP enzymatic activity and increased formation of PARP-DNA complexes resulting in DNA damage, apoptosis and cell death.



According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017


1.1 GHS Product identifier

Product name Niraparib

1.2 Other means of identification

Product number -
Other names MK4827

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1038915-60-4 SDS

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