1038916-11-8 Usage
General Description
Tert-butyl (3S)-3-{4-[7-(aminocarbonyl)-2H-indazol-2-yl]phenyl}piperidine-1-carboxylate is a chemical compound consisting of a piperidine ring attached to a benzene ring and an indazole ring. It has a tert-butyl group at the nitrogen of the piperidine ring and an aminocarbonyl group attached to the indazole ring. tert-butyl (3S)-3-{4-[7-(aminocarbonyl)-2H-indazol-2-yl]phenyl}piperidine-1-carboxylate is a piperidine derivative with potential pharmaceutical applications due to its structural features, which could interact with biological receptors or enzymes. Its molecular structure suggests a potential role in modulating cellular processes and potentially serving as a drug candidate for various biological targets. Further research is needed to investigate the pharmacological properties and potential therapeutic applications of tert-butyl (3S)-3-{4-[7-(aminocarbonyl)-2H-indazol-2-yl]phenyl}piperidine-1-carboxylate.
Check Digit Verification of cas no
The CAS Registry Mumber 1038916-11-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,3,8,9,1 and 6 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1038916-11:
(9*1)+(8*0)+(7*3)+(6*8)+(5*9)+(4*1)+(3*6)+(2*1)+(1*1)=148
148 % 10 = 8
So 1038916-11-8 is a valid CAS Registry Number.
1038916-11-8Relevant articles and documents
PROCESSES FOR THE PREPARATION OF NIRAPARIB AND INTERMEDIATES THEREOF
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, (2019/03/05)
The present invention relates to novel procedures and novel intermediates useful in the synthesis of Niraparib or any salt thereof.
PHARMACEUTICALLY ACCEPTABLE SALTS OF 2-{4-[(3S)-PIPERIDIN-3- YL]PHENYL} -2H-INDAZOLE-7-CARBOXAMIDE
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Page/Page column 39, (2009/09/04)
The present invention relates to pharmaceutically acceptable salts of an amide substituted indazole which are inhibitors of the enzyme poly(ADP-ribose)polymerase (PARP), previously known as poly(ADP-ribose)synthase and poly(ADP-ribosyl)transferase. The compounds of the present invention are useful as mono-therapies in tumors with specific defects in DNA-repair pathways and as enhancers of certain DNA -damaging agents such as anticancer agents and radiotherapy. Further, the compounds of the present invention are useful for reducing cell necrosis (in stroke and myocardial infarction), down regulating inflammation and tissue injury, treating retroviral infections and protecting against the toxicity of chemotherapy.
