1038919-75-3

Upstream product

• 34598-49-7 5-Bromo-1-indanone 
• 1038919-74-2 (S)-5-benzyl-3-(5-bromo-2,3-dihydro-1H-inden-1-yl)-2-ethyl-7-methyl-3H-imidazo[4,5-b]pyridine 
• 144873-97-2 2-(N-triphenylmethyl-tetrazol-5-yl)-phenylboronic acid 
• 1038919-63-9 (R)-5-bromo-2,3-dihydro-1H-inden-1-ol 
• 1038919-72-0 5-benzyl-2-ethyl-7-methyl-3H-imidazo[4,5-b]pyridine 

Downstream Products

• 1038919-67-3 (S)-3-(5-(2-(1H-tetrazol-5-yl)phenyl)-2,3-dihydro-1H-inden-1-yl)-5-benzyl-2-ethyl-7-methyl-3H-imidazo[4,5-b]pyridine 

Relevant academic research and scientific papers

Discovery of a series of imidazo[4,5-b ]pyridines with dual activity at angiotensin II Type 1 receptor and peroxisome proliferator-activated receptor-γ

Mining of an in-house collection of angiotensin II type 1 receptor antagonists to identify compounds with activity at the peroxisome proliferator-activated receptor-γ (PPARγ) revealed a new series of imidazo[4,5-b]pyridines 2 possessing activity at these

COMPOUNDS HAVING BOTH ANGIOTENSIN II RECEPTOR ANTAGONISM AND PPARY ACTIVATING ACTIVITIES

Compounds of following formula (I) are provided that have both angiontensin Il receptor antagonist activity and PPARy agonist activity. Also provided are pharmaceutical compositions comprising the compounds and methods of treatment of diseases with the co