103893-16-9

Upstream product

• 34874-62-9 N-(3-methoxyphenyl)-di-n-butylamine 
• 68-12-2 N,N-dimethyl-formamide 
• 74-88-4 methyl iodide 
• 90-04-0 2-methoxy-phenylamine 

Downstream Products

• 129502-07-4 5-[1-(4-Dibutylamino-2-methoxy-phenyl)-meth-(Z)-ylidene]-imidazolidine-2,4-dione 
• 129502-12-1 5-[1-(4-Dibutylamino-2-methoxy-phenyl)-meth-(Z)-ylidene]-2-thioxo-imidazolidin-4-one 
• 129501-92-4 C₁₇H₂₈N₄OS 
• 129501-97-9 (Z)-2-Cyano-3-(4-dibutylamino-2-methoxy-phenyl)-acrylic acid ethyl ester 
• 129502-02-9 (Z)-2-Cyano-3-(4-dibutylamino-2-methoxy-phenyl)-acrylamide 
• 1256155-30-2 dibutyl[3-methoxy-4-[2-(thiophene-2-yl)vinyl]phenyl]amine 
• 1267606-20-1 3-[2-(4-dibutylamino-2-methoxyphenyl)vinyl]-2-butyl-5,5-dimethyl-2-cyclohexenone 
• 1267605-36-6 3-[2-(4-dibutylamino-2-methoxyphenyl)vinyl]-2-methoxy-5,5-dimethyl-2-cyclohexenone 
• 1267604-99-8 5-(4-dibutylamino-2-methoxyphenyl)-2,4-pentadienal 
• 1267604-96-5 5-(4-dibutylamino-2-methoxyphenyl)-2,4-pentadienenitrile 
• 1267604-95-4 2-[4-[4-(4-dibutylamino-2-methoxyphenyl)-1,3-butadienyl]-3-cyano-5-phenyl-5-trifluoromethyl-2(5H)-furanylidene]propanedinitrile 
• 1267604-94-3 2-[4-[4-(4-dibutylamino-2-methoxyphenyl)-1,3-butadienyl]-3-cyano-5-methyl-5-trifluoromethyl-2(5H)-furanylidene]propanedinitrile 
• 1267604-93-2 2-[4-[4-(4-dibutylamino-2-methoxyphenyl)-1,3-butadienyl]-3-cyano-5,5-dimethyl-2(5H)-furanylidene]propanedinitrile 
• 1267604-92-1 3-(4-dibutylamino-2-methoxyphenyl)propenal 

Relevant academic research and scientific papers

Monocarboxylate transporter 1 inhibitors as potential anticancer agents

Potent monocarboxylate transporter 1 inhibitors (MCT1) have been developed based on α-cyano-4-hydroxycinnamic acid template. Structure-activity relationship studies demonstrate that the introduction of p-N, N-dialkyl/diaryl, and o-methoxy groups into cyanocinnamic acid has maximal MCT1 inhibitory activity. Systemic toxicity studies in healthy ICR mice with few potent MCT1 inhibitors indicate normal body weight gains in treated animals. In vivo tumor growth inhibition studies in colorectal adenocarcinoma (WiDr cell line) in nude mice xenograft models establish that compound 27 exhibits single agent activity in inhibiting the tumor growth.

SECOND-ORDER NONLINEAR OPTICAL COMPOUND AND NONLINEAR OPTICAL ELEMENT COMPRISING THE SAME

Problem to Be Solved: to provide a chromophore having a far superior nonlinear optical activity to conventional chromophores and to provide a nonlinear optical element comprising said chromophore. Solution: a chromophore comprising a donor structure D, a π-conjugated bridge structure B, and an acceptor structure A, the donor structure D comprising an aryl group substituted with a substituted oxy group; and a nonlinear optical element comprising said chromophore.

Effect of modified donor units on molecular hyperpolarizability of thienyl-vinylene nonlinear optical chromophores

Highly efficient and thermally stable nonlinear optical chromophores based on the phenyl vinylene thiophene vinylene (FTC) donor-π-acceptor structure have been synthesized and investigated. The donor part of the chromophores was modified with additional d