1038993-96-2Relevant academic research and scientific papers
Design and synthesis of macrocyclic peptidyl hydroxamates as peptide deformylase inhibitors
Shen, Gang,Zhu, Jinge,Simpson, Anthony M.,Pei, Dehua
, p. 3060 - 3063 (2008)
Macrocyclic peptidyl hydroxamates were designed, synthesized, and evaluated as peptide deformylase (PDF) inhibitors. The most potent compound exhibited tight, slow-binding inhibition of Escherichia coli PDF (KI* = 4.4 nM) and had pot
