1039115-89-3Relevant academic research and scientific papers
Selective head-to-tail recognition in hydrazide-based molecular duplex strands induced by spectator secondary electrostatic interactions
Yang, Yong,Xiang, Jun-Feng,Xue, Min,Hu, Hai-Yu,Chen, Chuan-Feng
, p. 4198 - 4203 (2008)
Due to spectator secondary electrostatic interactions, nonsymmetric mono-Boc-mono-acetyl terminated hydrazide-based oligomers displayed a head-to-tail dimerization mode, which was evidenced by 1H NMR, and 2D NOESY experiments. Dynamic behavior of the molecular duplex strands was also explored by variable temperature 1H NMR experiments.
Supramolecular substitution reactions between hydrazide-based molecular duplex strands: Complexation induced nonsymmetry and dynamic behavior
Yang, Yong,Xiang, Jun-Feng,Xue, Min,Hu, Hai-Yu,Chen, Chuan-Feng
, p. 6369 - 6377 (2008/12/22)
(Chemical Equation Presented) Supramolecular substitution reactions between hydrazide-based oligomers 1a-c and 2a-c were systematically investigated. Each oligomer existed as hydrogen-bonding mediated molecular duplex strands or a polymeric zipper structure in apolar solvents. But when another oligomer with complementary hydrogen bonding sites was added, a heterodimer structure formed due to supramolecular substitution reaction driven by the formation of more hydrogen bonds, which was evidenced by NMR experiments, sometimes gel-sol transition. When a nonsymmetric oligomer and a symmetric oligomer were involved, complexation-induced nonsymmetry was observed. When two nonsymmetric oligomers were involved, two hydrogen-bonded isomers were observed in solution. Variable-temperature 1H NMR experiments further revealed unique dynamic behavior for the individual oligomer and the complexes. When diacetyl-terminated oligomer 1c was involved, slides perpendicular to hydrogen bonds between two constituent molecules were observed, which led to complicated 1H NMR spectra at lower temperature; otherwise, high selectivity was obtained. Combined with the results we reported previously, a detailed picture of the structure-property relationship for our hydrazide-based oligomers was depicted, which would provide guidelines for the design of hydrazide-based fine-tuning functional materials.
