1039136-82-7Relevant academic research and scientific papers
Solution-, solid-phase, and fluorous synthesis of β,β- difluorinated cyclic quaternary a-amino acid derivatives: A comparative study
Fustero, Santos,Sanchez-Rosello, Maria,Rodrigo, Vanessa,Sanz-Cervera, Juan F.,Piera, Julio,Simon-Fuentes, Antonio,Del Pozo, Carlos
experimental part, p. 7019 - 7029 (2009/08/07)
The diastereoselective synthesis of cyclic β,β-difluorinated α-amino acid derivatives bearing a quaternary stereocenter is described. The process relies on the chemo- and diastereoselective addition of allylic organometallic reagents to fluorinated αimino
Selective formal transesterification of fluorinated 2-(trimethylsilyl)ethyl α-imino esters mediated by TBAF
Fustero, Santos,Sanchez-Rosello, Maria,Rodrigo, Vanessa,Garcia, Amador,Catalan, Silvia,Del Pozo, Carlos
, p. 5617 - 5620 (2008/12/21)
(Chemical Equation Presented) The scope of the transesterification reaction between β-fluorinated α-imino esters and various electrophiles in the presence of TBAF as fluorine source is described. The reaction is highly selective for alkyl iodides, bromide
