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Beta-Estradiol-3-sulfate-17-glucopyranosiduronic acid dipotassium salt, also known as estradiol 3-sulfate 17β-glucuronide, is a metabolite of the steroid hormone 17β-estradiol. It is a sulfated and glucuronidated form of estradiol 3-sulfate, which is common in fetal plasma and breast tissues of patients with mammary carcinoma. beta-Estradiol-3-sulfate-17-glucopyranosiduronic acid dipotassium salt can be converted back to the parent compound by sulfatases and has enhanced utilization by anion transporters, leading to excretion in urine and bile. It is a white to off-white solid.

10392-35-5

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10392-35-5 Usage

Uses

Used in Pharmaceutical Industry:
Beta-Estradiol-3-sulfate-17-glucopyranosiduronic acid dipotassium salt is used as a pharmaceutical intermediate for the synthesis of various estrogen-based drugs. Its sulfated and glucuronidated forms provide enhanced bioavailability and targeted delivery to specific tissues, making it a valuable compound in the development of hormone replacement therapies and treatments for menopausal symptoms.
Used in Research Applications:
In the field of research, beta-Estradiol-3-sulfate-17-glucopyranosiduronic acid dipotassium salt serves as an important tool for studying the metabolism, transport, and excretion of estrogens. It helps researchers understand the role of sulfatases and UDP-glucuronosyltransferases in the conversion and elimination of estrogens, providing insights into the development of targeted therapies for hormone-related disorders.
Used in Diagnostic Applications:
Beta-Estradiol-3-sulfate-17-glucopyranosiduronic acid dipotassium salt can be used as a diagnostic marker for various hormone-related conditions, including menopause, hormone imbalances, and breast cancer. Its presence in biological samples can be detected and quantified using analytical techniques such as mass spectrometry, providing valuable information for the assessment and monitoring of these conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 10392-35-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,3,9 and 2 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 10392-35:
(7*1)+(6*0)+(5*3)+(4*9)+(3*2)+(2*3)+(1*5)=75
75 % 10 = 5
So 10392-35-5 is a valid CAS Registry Number.

10392-35-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name Estradiol 3-Sulfate 17β-Glucuronide Dipotassium Salt

1.2 Other means of identification

Product number -
Other names β-Estradiol-3-sulfate-17-glucopyranosiduronic acid dipotassium salt

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:10392-35-5 SDS

10392-35-5Upstream product

10392-35-5Downstream Products

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