103929-50-6

Basic information

• Product Name: 2(1H)-Quinolinone,4-hydroxy-8-methoxy-3-phenyl-
• Synonyms: 4-hydroxy-8-methoxy-3-phenyl-2(1H)-quinolinone
• CAS NO: 103929-50-6
• Molecular Formula: C₁₆H₁₃NO₃
• Molecular Weight: 267.2793
• Mol File: 103929-50-6.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 455.8°Cat760mmHg
• Flash Point: 229.5°C
• Appearance: /
• Density: 1.315g/cm³
• Vapor Pressure: 4.22E-09mmHg at 25°C
• Refractive Index: 1.65
• CAS DataBase Reference: 2(1H)-Quinolinone,4-hydroxy-8-methoxy-3-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2(1H)-Quinolinone,4-hydroxy-8-methoxy-3-phenyl-(103929-50-6)
• EPA Substance Registry System: 2(1H)-Quinolinone,4-hydroxy-8-methoxy-3-phenyl-(103929-50-6)

Safety Data

• Hazardous Substances Data: 103929-50-6(Hazardous Substances Data)

Usage

Structure

Derivative of quinolinone with a hydroxyl group, a methoxy group, and a phenyl group

Pharmaceutical applications

Potential use as an antitumor agent

Biological activities

Possible other activities, but further research is needed to fully understand its potential uses and effects

InChI:InChI=1/C16H13NO3/c1-20-12-9-5-8-11-14(12)17-16(19)13(15(11)18)10-6-3-2-4-7-10/h2-9H,1H3,(H2,17,18,19)

Upstream product

• 90-04-0 2-methoxy-phenylamine 
• 83-13-6 diethyl 2-phenylmalonate 
• 1227736-34-6 3-phenyl-8-methoxy-4-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyloxy)quinolin-2(1H)-one 
• 104-94-9 4-methoxy-aniline 

Downstream Products

• 1227736-34-6 3-phenyl-8-methoxy-4-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyloxy)quinolin-2(1H)-one 
• 144603-90-7 3-Fluoro-8-methoxy-3-phenyl-1H-quinoline-2,4-dione 
• 144603-18-9 3-Bromo-8-methoxy-3-phenyl-1H-quinoline-2,4-dione 
• 144603-50-9 3-Chloro-8-methoxy-3-phenyl-1H-quinoline-2,4-dione 

Relevant articles and documents

Rapid microwave-enhanced synthesis of 4-hydroxyquinolinones under solvent-free conditions

3-Aryl-4-hydroxyquinolin-2(1H)-ones are potent and selective glycine-site NMDA receptor antagonists of pharmaceutical interest. A novel microwave-enhanced synthesis of such quinolinones under solvent-free conditions has been developed. The quinolinones ar

Selective formation of glycosidic linkages of N-unsubstituted 4-hydroxyquinolin-2-(1H)-ones

A comparative study for selective glucosylation of N-unsubstituted 4-hydroxyquinolin-2(1H)-ones into 4-(tetra-O-acetyl-β-d-glucopyranosyloxy)quinolin-2(1H)-ones is reported. Four glycosyl donors including tetra-O-acetyl-α-d-glucopyranosyl bromide, β-d-glu

Oxidative Hydroxylation of Heterocyclic β-Dicarbonyl Compounds

3-Substituted 4-hydroxy-2-quinolones (1), 5-substituted barbituric acids (3) and 4-substituted pyrazolidine-2,4-diones were oxidized to yield the corresponding hydroxyderivatives 2,4 or 9, respectively. - Keywords: 5-Hydroxy-2,4,6-pyrimidine-triones; 4-Hy