103954-23-0

Basic information

• Product Name: N²-(1-D-carboxyethyl)-L-phenylalanine
• Synonyms: N²-(1-D-carboxyethyl)-L-phenylalanine
• CAS NO: 103954-23-0
• Molecular Weight: 273.716
• Mol File: 103954-23-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N²-(1-D-carboxyethyl)-L-phenylalanine(CAS DataBase Reference)
• NIST Chemistry Reference: N²-(1-D-carboxyethyl)-L-phenylalanine(103954-23-0)
• EPA Substance Registry System: N²-(1-D-carboxyethyl)-L-phenylalanine(103954-23-0)

Safety Data

• Hazardous Substances Data: 103954-23-0(Hazardous Substances Data)

Upstream product

• 2577-90-4 methyl (2S)-2-amino-3-phenylpropanoate 
• 84028-88-6 ethyl (S)-lactate triflate 
• 7524-50-7 methyl (2S)-2-amino-3-phenylpropanoate hydrochloride 

Relevant articles and documents

A General Stereocontrolled Synthesis of Opines through Asymmetric Pd-Catalyzed N-Allylation of Amino Acid Esters

A stereo-divergent synthesis of natural and unnatural opines in stereochemically pure form is based on the direct palladium-catalyzed N-allylation of α-amino acid esters (up to 97 % ee or 99 : 1 d.r.) using methyl (E)-2-penten-4-yl carbonate in the presence of only 1 mol% of a catalyst, prepared in-situ from the C2-symmetric diphosphine iPr-MediPhos and [Pd(allyl)Cl]2. Selected target compounds (incl. a derivative of the drug enalapril) were efficiently obtained from the N-allylated intermediates by oxidative cleavage (ozonolysis) of the allylic C=C bond under temporary N-Boc-protection.