1039540-65-2Relevant academic research and scientific papers
4″-benzoylureido-TSAO derivatives as potent and selective non-nucleoside HCMV inhibitors. Structure-activity relationship and mechanism of antiviral action
De Castro, Sonia,Peromingo, M. Teresa,Naesens, Lieve,Andrei, Graciela,Snoeck, Robert,Balzarini, Jan,Velázquez, Sonsoles,Camarasa, María-José
experimental part, p. 5823 - 5832 (2009/09/08)
Analogues of the 4″-benzoyl-ureido-TSAO derivative (1) modified at different positions have been prepared and evaluated against wild-type strains of HCMV and murine cytomegalovirus (MCMV) in cell culture. In addition, the activity of the most active deriv
Novel non-nucleoside human cytomegalovirus inhibitors based upon TSAO nucleoside derivatives: Structure-activity relationships
De Castro, Sonia,Andrei, Graziela,Snoeck, Robert,Balzarini, Jan,Camarasa, Maria-Jose,Velazquez, Sonsoles
, p. 625 - 628 (2008/09/17)
TSAO derivatives are a unique group of potent and highly specific inhibitors of HIV-1 replication. We have recently reported 4′-ureido TSAO derivatives that are devoid of anti-HIV-1 activity, but inhibit human cytomegalovirus with an activity comparable t
