10396-14-2

Upstream product

• 563-41-7 semicarbazide hydrochloride 
• 121-60-8 p-acetylaminobenzenesulfonyl chloride 
• 123-77-3 1,1'-azobisformamide 
• 710-24-7 4-acetamidobenzenesulfinic acid 
• 57049-47-5 1-p-Acetamidobenzolsulfonyl-1,2-diazandicarboxamid 

Downstream Products

• 4938-14-1 1-sulfanilyl semicarbazide 

Relevant academic research and scientific papers

A convenient procedure for the preparation of sulfonamidoureas using triphosgene

An efficient method for the preparation of sulfonamidourea using triphosgene in organic solvents is reported. Sulfonylhydrazides and acetylsulfanilylhydrazide were transformed into the corresponding intermediates using triphosgene in 1,4-dioxane/water or tetrahydrofuran as solvents. These intermediates were converted in situ into symmetrical and unsymmetrical sulfonamidoureas in high yields and shorter periods of time related to previous methods.

Method for producing sulfonyl semicarbazides

A new synthetic route to sulfonyl semicarbazides wherein an azobisformamide is reacted with a free sulfinic acid.