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4,6-dichloro-N-isopropylpyrimidin-2-amine is a pyrimidine derivative chemical compound characterized by the molecular formula C9H11Cl2N3. It features a pyrimidine ring with two chlorine atoms at the 4th and 6th positions and an isopropyl group attached to the second position. 4,6-dichloro-N-isopropylpyriMidin-2-aMine holds potential in the pharmaceutical and agrochemical industries, primarily as an intermediate in the synthesis of various drugs and agrochemicals. Its unique structure may also endow it with biological activity, positioning it as a potential drug lead or a foundation for developing new therapeutic agents. However, due to its chemical properties, careful handling and usage are advised to mitigate any associated risks.

10397-16-7

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10397-16-7 Usage

Uses

Used in Pharmaceutical Industry:
4,6-dichloro-N-isopropylpyrimidin-2-amine is used as a chemical intermediate for the synthesis of pharmaceutical drugs. Its unique structure allows for the development of new compounds with potential therapeutic effects, making it a valuable asset in drug discovery and medicinal chemistry.
Used in Agrochemical Industry:
In the agrochemical sector, 4,6-dichloro-N-isopropylpyrimidin-2-amine serves as an intermediate in the production of various agrochemicals. Its incorporation into these products can contribute to the creation of more effective pesticides, herbicides, or other agricultural chemicals that enhance crop protection and yield.
Used as a Drug Lead:
Due to its potential biological activity, 4,6-dichloro-N-isopropylpyrimidin-2-amine may be utilized as a drug lead. Researchers can explore its interactions with biological targets to identify possible applications in treating diseases or conditions, furthering the development of novel therapeutic agents.
Used in Chemical Research:
4,6-dichloro-N-isopropylpyriMidin-2-aMine can also be employed in chemical research to study the effects of structural modifications on biological activity and pharmacological properties. Understanding these relationships can guide the design of more effective and safer drugs and agrochemicals.

Check Digit Verification of cas no

The CAS Registry Mumber 10397-16-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,3,9 and 7 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 10397-16:
(7*1)+(6*0)+(5*3)+(4*9)+(3*7)+(2*1)+(1*6)=87
87 % 10 = 7
So 10397-16-7 is a valid CAS Registry Number.

10397-16-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 4,6-dichloro-N-propan-2-ylpyrimidin-2-amine

1.2 Other means of identification

Product number -
Other names 4,6-dichloro-N-isopropylpyrimidin-2-amine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:10397-16-7 SDS

10397-16-7Downstream Products

10397-16-7Relevant academic research and scientific papers

AZOLOPYRIMIDINE FOR THE TREATMENT OF CANCER-RELATED DISORDERS

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Paragraph 0720, (2018/08/12)

Compound that is an inhibitor of at least one of the A2A and A2B adenosine receptors, and compositions containing the compound and methods for synthesizing the compound, are described herein. The use of such compound and compositions for the treatment of a diverse array of diseases, disorders, and conditions, including cancer- and immune-related disorders that are mediated, at least in part, by the adenosine A2A receptor and/or the adenosine A2B receptor.

2,4- OR 4,6-DIAMINOPYRIMIDINE COMPOUNDS AS IDH2 MUTANTS INHIBITORS FOR THE TREATMENT OF CANCER

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Page/Page column 135, (2015/02/02)

Provided are compounds of formula (I), wherein: ring A and ring B are each independently an optionally substituted 5-6 membered monocyclic aryl or heteroaryl; one of X, Y and W is CH and the two others are N; and Z is H or -C(R1)(R2)(R3). The compounds are inhibitors of isocitrate dehydronenase 2 (IDH2) mutants useful for treating cancer.

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