1039747-95-9Relevant academic research and scientific papers
Pd-catalyzed sequential reactions via allene intermediate for the synthesis of polycyclic frameworks containing 2,3-dihydrofuran units
Shen, Ruwei,Huang, Xian
supporting information; experimental part, p. 3283 - 3286 (2009/05/11)
(Chemical Equation Presented) A stepwise process involving Sonogashira coupling, propargyl allenyl isomerization, and consecutive [4 + 2] cyclization has been realized, leading to an efficient synthesis of polycyclic compounds containing a 2,3-dihydrofuran unit. Most attractive for synthetic interest is the finding that up to four stereogenic centers could be generated in one step with high stereoselectivity.
