Cas 1039760-80-9,(1E,6E)-4-(3,4-dimethoxybenzylidene)-1,7-bis(3,4-dimethoxyphenyl)hepta-1,6-diene-3,5-dione

1039760-80-9

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Basic information

Product Name: (1E,6E)-4-(3,4-dimethoxybenzylidene)-1,7-bis(3,4-dimethoxyphenyl)hepta-1,6-diene-3,5-dione
Synonyms: (1E,6E)-4-(3,4-dimethoxybenzylidene)-1,7-bis(3,4-dimethoxyphenyl)hepta-1,6-diene-3,5-dione
CAS NO:1039760-80-9
Molecular Formula:
Molecular Weight: 544.601
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: (1E,6E)-4-(3,4-dimethoxybenzylidene)-1,7-bis(3,4-dimethoxyphenyl)hepta-1,6-diene-3,5-dione(CAS DataBase Reference)
NIST Chemistry Reference: (1E,6E)-4-(3,4-dimethoxybenzylidene)-1,7-bis(3,4-dimethoxyphenyl)hepta-1,6-diene-3,5-dione(1039760-80-9)
EPA Substance Registry System: (1E,6E)-4-(3,4-dimethoxybenzylidene)-1,7-bis(3,4-dimethoxyphenyl)hepta-1,6-diene-3,5-dione(1039760-80-9)

Safety Data

Hazard Codes: N/A
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Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 1039760-80-9(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 1039760-80-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,3,9,7,6 and 0 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1039760-80:
(9*1)+(8*0)+(7*3)+(6*9)+(5*7)+(4*6)+(3*0)+(2*8)+(1*0)=159
159 % 10 = 9
So 1039760-80-9 is a valid CAS Registry Number.

1039760-80-9Upstream product

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1039760-80-9Relevant academic research and scientific papers

Synthesis and identification of new 4-arylidene curcumin analogues as potential anticancer agents targeting nuclear factor-κB signaling pathway

Qiu, Xu,Du, Yuhong,Lou, Bin,Zuo, Yinglin,Shao, Weiyan,Huo, Yingpeng,Huang, Jianing,Yu, Yanjun,Zhou, Binhua,Du, Jun,Fu, Haian,Bu, Xianzhang

experimental part, p. 8260 - 8273 (2011/02/21)

A series of curcumin analogues including new 4-arylidene curcumin analogues (4-arylidene-1,7-bisarylhepta-1,6-diene-3,5-diones) were synthesized. Cell growth inhibition assays revealed that most 4-arylidene curcumin analogues can effectively decrease the growth of a panel of lung cancer cells at submicromolar and low micromolar concentrations. High content analysis technology coupled with biochemical studies showed that this new class of 4-arylidene curcumin analogues exhibits significantly improved NF-κB inhibition activity over the parent compound curcumin, at least in part by inhibiting IκB phosphorylation and degradation via IKK blockage; selected 4-arylidene curcumin analogues also reduced the tumorigenic potential of cancer cells in a clonogenic assay.

COMPOUNDS WITH (SUBSTITUTED PHENYL)-PROPENAL MOIETY, THEIR DERIVATIVES, BIOLOGICAL ACTIVITY, AND USES THEREOF

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Page/Page column 40; 44, (2008/12/07)

The present invention includes compounds, pharmaceuticals and cosmetics having at least one (substituted phenyl)-propenal moiety. The compounds and compositions of the present invention are useful in the treatment or prevention of many medical conditions such as androgen associated conditions. The present invention also includes methods of treating a medical condition including an androgen associated condition, using at least one of the disclosed compounds.

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