103979-75-5Relevant academic research and scientific papers
Synthesis of Optically Active (-)-Trachelanthamidine from L-Prolinol
Ishibashi, Hiroyuki,Ozeki, Hiromi,Ikeda, Masazumi
, p. 654 - 655 (1986)
(-)-Trachelanthamidine was synthesised in an optically active form from L-prolinol, using olefin cyclisation initiated by an α-thiocarbocation as the key step.
Carbamoylmethyl radical cyclization: Formal synthesis of (-)-trachelanthamidine
Sato,Tsujimoto,Matsubayashi,Ishibashi,Ikeda
, p. 2308 - 2312 (2007/10/02)
Tributyltin hydride-mediated radical cyclization of the (2S)-N-(α-chloroacetyl)-2-ethenylpyrrolidines 13a, b and 15 and the bis(phenylthio)acetyl congener 14 derived from (S)-prolinol gave (1R,7aS)-hexahydro-1-methyl-3H-pyrrolizin-3-one (17) and its deriv
