1039803-54-7Relevant articles and documents
LIPOXYGENASE INHIBITORS
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Paragraph 00431, (2021/07/02)
Various embodiments of the present disclosure are directed to compounds having Formula I, Formula II, Formula IIA, Formula III, Formula IIIA, Formula IIIB, and/or pharmaceutically acceptable salts thereof. The compounds can be suitable for inhibiting lipoxygenases and/or treating associated diseases. In some embodiments, subject compounds are used to prepare a composition that is effective in treating neurodegenerative diseases.
Substituted N-(2-aminophenyl)-benzamides, (E)-N-(2-aminophenyl)-acrylamides and their analogues: Novel classes of histone deacetylase inhibitors
Moradei, Oscar,Leit, Silvana,Zhou, Nancy,Frechette, Sylvie,Paquin, Isabelle,Raeppel, Stephane,Gaudette, Frederic,Bouchain, Giliane,Woo, Soon H.,Vaisburg, Arkadii,Fournel, Marielle,Kalita, Ann,Lu, Aihua,Trachy-Bourget, Marie-Claude,Yan, Pu T.,Liu, Jianhong,Li, Zuomei,Rahil, Jubrail,MacLeod, A. Robert,Besterman, Jeffrey M.,Delorme, Daniel
, p. 4048 - 4052 (2007/10/03)
Inhibition of histone deacetylases (HDACs) is emerging as a new strategy in human cancer therapy. Novel 2-aminophenyl benzamides and acrylamides, that can inhibit human HDAC enzymes and induce hyperacetylation of histones in human cancer cells, have been