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104010-37-9

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104010-37-9 Usage

Brand Name(s) in US

Naxcel

Third-generation cephalosporins

Ceftiofur sodium is the sodium salt of ceftiofur, which belongs to the third generation cephalosporin antibiotics, for the first time in 1988 it was listed in the United States. Chemical properties are stabie, appearance is light yellow to white crystalline powder, aqueous solution has a shorter retention time, it should be diluted into a solution before use. Ceftiofur has a broad antimicrobial spectrum , it has a strong antibacterial activity , it has a strong antibacterial activity against Gram-positive bacteria, Gram-negative bacteria, and some anaerobic bacteria ,its antibacterial activity is similar to or weaker than the first-generation cephalosporins against Gram-positive bacteria , it has a strong antibacterial activity against Gram-negative bacteria such as E. coli, Salmonella, Pasteurella and so on. It is used for a variety of respiratory, urinary tract and other infections caused by sensitive bacteria, especially for the prevention and treatment of early death of chicks caused by E. coli, Salmonella, Pseudomonas aeruginosa, Staphylococcus aureus , E. coli yellow dysentery of 1 piglets and wound infections caused by cutting the umbilical cord, ear numbers, cutting teeth, tails and others, pleuropneumoniae and bovine bronchial pneumonia caused by Haemophilus and Actinobacillus , generally it does not apply to cows and goats mastitis treatment . Some researchers have done ceftiofur sodium inhibition tests for thousands strains of pathogens isolated by veterinary clinically , the results show that the drug is one of the most active anti-bacterial drugs, it has a strong antibacterial activity against Escherichia coli, p.multocida and p.haemolytica ,Bacillus typhosus, Streptococcus ; it also has a good effect on Pseudomonas aeruginosa, Enterobacter, anaerobic bacteria. It is used for the treatment of respiratory disease of sheep,horses, cattle, pigs (pleuropneumonia),and the treatment of pets, day-old broiler infectious diseases. This product has characteristics such as complete intramuscular absorption and long elimination half-life period . The above information is edited by the lookchem of Tian Ye.

Uses

Different sources of media describe the Uses of 104010-37-9 differently. You can refer to the following data:
1. It belongs to antibiotic medicines for the treatment of swine bacterial respiratory infection
2. Antibacterial (veterinary).
3. Ceftiofur sodium is resistant to the antibiotic resistance enzyme beta-lactamase, and has activity against Gram-positive and Gram-negative bacteria. E. coli strains resistant to ceftiofur have been reported. The bactericidal activity of ceftiofur results from the inhibition of cell wall synthesis via affinity for penicillin-binding proteins. The PBPs are transpeptidases which are vital in peptidoglycan biosynthesis. Therefore, their inhibition prevents this vital cell wall component from being properly synthesized.

Chemical Properties

White or light yellow crystalline powder

Veterinary Drugs and Treatments

Labeled indications for ceftiofur sodium: In cattle for treatment of bovine respiratory disease (shipping fever, pneumonia) associated with Mannheimia haemolytica, Pasteurella multocida and Histophilus somni. It is also indicated for treatment of acute bovine interdigital necrobacillosis (foot rot, pododermatitis) associated with Fusobacterium necrophorum and Bacteroides melaninogenicus. In swine for treatment/control of swine bacterial respiratory disease (swine bacterial pneumonia) associated with Actinobacillus (Haemophilus) pleuropneumoniae, Pasteurella multocida, Salmonella choleraesuis and Streptococcus suis. In sheep/goats for treatment of sheep/caprine respiratory disease (sheep/goat pneumonia) associated with Mannheimia haemolytica and Pasteurella multocida. In horses for treatment of respiratory infections in horses associated with Streptococcus zooepidemicus. In dogs for the treatment of canine urinary tract infections associated with E. coli and Proteus mirabilis. In day old chicks/poults for the control of early mortality, associated with E. coli organisms susceptible to ceftiofur. Ceftiofur sodium has also been used in an extra-label manner in a variety of veterinary species (see Doses) to treat infections that likely to be susceptible to a 3rd generation cephalosporin.

Check Digit Verification of cas no

The CAS Registry Mumber 104010-37-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,4,0,1 and 0 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 104010-37:
(8*1)+(7*0)+(6*4)+(5*0)+(4*1)+(3*0)+(2*3)+(1*7)=49
49 % 10 = 9
So 104010-37-9 is a valid CAS Registry Number.
InChI:InChI=1/C19H17N5O7S3.Na/c1-30-23-11(9-7-34-19(20)21-9)14(25)22-12-15(26)24-13(17(27)28)8(5-32-16(12)24)6-33-18(29)10-3-2-4-31-10;/h2-4,7,12,16H,5-6H2,1H3,(H2,20,21)(H,22,25)(H,27,28);/q;+1/p-1/b23-11-;/t12-,16-;/m1./s1

104010-37-9 Well-known Company Product Price

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  • USP

  • (1098082)  Ceftiofur sodium  United States Pharmacopeia (USP) Reference Standard

  • 104010-37-9

  • 1098082-100MG

  • 4,647.24CNY

  • Detail

104010-37-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name Ceftiofur sodium salt

1.2 Other means of identification

Product number -
Other names Sodium ceftiofur

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:104010-37-9 SDS

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104010-37-9Related news

Highly efficient removal of Ceftiofur sodium (cas 104010-37-9) using a superior hydroxyl group functionalized ionic liquid-modified polymer07/29/2019

The occurrence of cephalosporin antibiotics in water resources has caused increasing concerns about their potential effects on ecosystem and human health. However, reports on the efficient removal of these antibiotics are limited. In this work, a superior hydroxyl-functionalized ionic liquid bas...detailed

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