1040101-95-8

Upstream product

• 42142-15-4 1-(4-nitro-phenyl)-ethylamine 
• 172153-32-1 tert-butyl (1-(4-nitrophenyl)ethyl)carbamate 
• 643086-68-4 [1-(4-amino-phenyl)-ethyl]carbamic acid tert-butyl ester 
• 921604-46-8 (1-{4-[5-(2-oxo-hexahydro-thieno[3,4-d]imidazol-6-yl)-pentanoylamino]-phenyl}-ethyl)-carbamic acid tert-butyl ester 

Relevant academic research and scientific papers

4-Aminopyrimidines as novel HIV-1 inhibitors

A series of 4-aminopyrimidines (1) was identified as novel HIV inhibitors of unknown molecular target. Structural modifications were carried out to establish its SAR and identify the linking site for target identification. A number of analogs were found to possess single digit inhibitory activity for HIV replication. Several analogs with various potential linkers, including a biotinated analog, also exhibited excellent potency, and could serve as tools for the identification of novel anti-HIV targets.