104021-84-3

Upstream product

• 114995-96-9 (1S,2R)-<1-(1-methoxy-4-oxo-2-azetidinyl)-3-methylbutyl>carbamic acid 1,1-dimethylethyl ester 
• 114995-94-7 (1S,2S)-<2-hydroxy-4-(methoxyamino)-1-(2-methylpropyl)-4-oxobutyl>carbamic acid 1,1-dimethylethyl ester 
• 115017-05-5 (1S,2R)-<1-(4-oxo-2-azetidinyl)-3-methylbutyl>carbamic acid 1,1-dimethylethyl ester 
• 104021-46-7 (3R,4S)-3-Amino-4-tert-butoxycarbonylamino-6-methyl-heptanoic acid 
• 104021-85-4 (3R,4S)-4-<<(1,1-dimethylethoxy)carbonyl>amino>-6-methyl-3-<<(phenylmethoxy)carbonyl>amino>heptanoic acid 
• 74-88-4 methyl iodide 
• 58521-49-6 (3S,4S)-4-(tert-butoxycarbonylamino)-3-hydroxy-6-methylheptanoic acid 
• 118585-36-7 Methanesulfonic acid (1S,2S)-2-tert-butoxycarbonylamino-1-(methoxycarbamoyl-methyl)-4-methyl-pentyl ester 

Downstream Products

• 115073-56-8 (4R,5S)-4-<<(phenylmethoxy)carbonyl>amino>-5-(2'-methylpropyl)-2-oxopyrrolidine 

Relevant academic research and scientific papers

Application of the N-hydroxymethyl group to the stereoselective synthesis of (3S,4S)-3-aminodeoxystatine derivatives

Stereoselective synthesis of two 3-aminodeoxystatine derivatives was achieved. Chiral γ-amino-α,β-unsaturated esters containing an N-aminomethyl group undergo the stereoselective conjugate addition with an internal carbamate or amide nitrogen nucleophile.