1040246-87-4

Basic information

• Product Name: 4,6-Dichloro-3-pyridazinecarboxylic acid
• Synonyms: 4,6-Dichloro-3-pyridazinecarboxylic acid;4,6-dichloropyridazine-3-carboxylic acid;4,6-Dichloro-pyridazin-3-carboxylic acid;,6-Dichloro-3-pyridazinecarboxylic acid;EOS-61511
• CAS NO: 1040246-87-4
• Molecular Formula: C₅H₂Cl₂N₂O₂
• Molecular Weight: 192.98758
• Mol File: 1040246-87-4.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 436.5±40.0 °C(Predicted)
• Appearance: /
• Density: 1.718±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 1.31±0.25(Predicted)
• CAS DataBase Reference: 4,6-Dichloro-3-pyridazinecarboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4,6-Dichloro-3-pyridazinecarboxylic acid(1040246-87-4)
• EPA Substance Registry System: 4,6-Dichloro-3-pyridazinecarboxylic acid(1040246-87-4)

Safety Data

• Hazardous Substances Data: 1040246-87-4(Hazardous Substances Data)

Usage

Uses

4,6-Dichloro-3-pyridazinecarboxylic Acid is an intermediate in preparation of N-Heteroarylsulfonamide derivative in the study of treatment of hyperproliferative diseases.

Upstream product

• 372118-01-9 4,6-dichloro-pyridazine-3-carboxylic acid methyl ester 

Downstream Products

• 1040246-88-5 4-(4-bromo-2-fluorophenylamino)-6-chloropyridazine-3-carboxylic acid 

Relevant articles and documents

SULFONE PYRIDINE ALKYL AMIDE-SUBSTITUTED HETEROARYL COMPOUNDS

Compounds having the following formula I: or a stereoisomer or pharmaceutically-acceptable salt thereof, where R1, R2, R3, R4, and R5 are as defined herein, are useful in the modulation of IL-12, IL-23 and/or IFNα, by acting on Tyk-2 to cause signal transduction inhibition.

INHIBITORS OF MEK

This invention concerns to N-(2-aylamino) aryl sulfonamides, which are inhibitors of MEK, methods of using such compounds in the treatment of hyperproliferative diseases, and to pharmaceutical compositions containing such compounds.