1040250-19-8

Basic information

• Product Name: OlMesartan DiMer Ester IMpurity
• Synonyms: OlMesartan DiMer Ester IMpurity;4-(1-Hydroxy-1-Methylethyl)-2-propyl-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]Methyl]-1H-iMidazole-5-carboxylic Acid;OlMesartan MedoxoMil iMpurity IV;OlMesartan DiMer Ester;OlMesartan DiMer Ester IMpurity Discontinued;Olmesartan medoxomil impurity Ⅳ;Olmesartan MedoxomiI Dimer Ether Impurity;4-(1-Hydroxy-1-methylethyl)-2-propyl-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylic acid 1-[5-carboxy-2-propyl-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazol-4-yl]-1-methylethyl ester
• CAS NO: 1040250-19-8
• Molecular Formula: C48H48N12O5
• Molecular Weight: 872.97212
• Product Categories: Aromatics;Bases & Related Reagents;Heterocycles;Impurities;Intermediates & Fine Chemicals;Nucleotides;Pharmaceuticals
• Mol File: 1040250-19-8.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 1101.2±75.0 °C(Predicted)
• Appearance: /
• Density: 1.35±0.1 g/cm3(Predicted)
• PKA: 2.13±0.50(Predicted)
• CAS DataBase Reference: OlMesartan DiMer Ester IMpurity(CAS DataBase Reference)
• NIST Chemistry Reference: OlMesartan DiMer Ester IMpurity(1040250-19-8)
• EPA Substance Registry System: OlMesartan DiMer Ester IMpurity(1040250-19-8)

Safety Data

• Hazardous Substances Data: 1040250-19-8(Hazardous Substances Data)

Usage

Description

Olmesartan Dimer Ester Impurity is a dimeric degradation product found in stressed tablets of Olmesartan (O550001). It is characterized by its off-white solid appearance.

Uses

Used in Pharmaceutical Industry:
Olmesartan Dimer Ester Impurity is used as a reference material for the identification and quantification of impurities in the manufacturing process of Olmesartan. This helps ensure the quality, safety, and efficacy of the final drug product by monitoring and controlling the presence of degradation products.
Used in Quality Control:
Olmesartan Dimer Ester Impurity is used as a quality control standard in the pharmaceutical industry. It aids in the development and validation of analytical methods, such as high-performance liquid chromatography (HPLC) and other chromatographic techniques, to accurately measure the impurity levels in Olmesartan drug products.
Used in Research and Development:
Olmesartan Dimer Ester Impurity is utilized in research and development for the study of the stability, degradation pathways, and potential side effects of Olmesartan. This information is crucial for the optimization of manufacturing processes, formulation development, and the overall improvement of the drug's performance and safety profile.