1040274-18-7

Usage

Uses

Used in Organic Synthesis:
Oxazole,2-[(1S)-7'-[bis[3,5-bis(1,1-dimethylethyl)phenyl]phosphino]-2,2',3,3'-tetrahydro-1,1'-spirobi[1H-inden]-7-yl]-4,5-dihydrois used as a building block or intermediate in organic synthesis for the development of new compounds with specific properties and functions.
Used in Catalysis:
Due to its unique structural features, including the presence of phosphine groups, Oxazole,2-[(1S)-7'-[bis[3,5-bis(1,1-dimethylethyl)phenyl]phosphino]-2,2',3,3'-tetrahydro-1,1'-spirobi[1H-inden]-7-yl]-4,5-dihydrocan be employed as a catalyst or catalyst precursor in various chemical reactions, enhancing their efficiency and selectivity.
Used in Materials Science:
The complex structure and chiral nature of Oxazole,2-[(1S)-7'-[bis[3,5-bis(1,1-dimethylethyl)phenyl]phosphino]-2,2',3,3'-tetrahydro-1,1'-spirobi[1H-inden]-7-yl]-4,5-dihydromake it a promising candidate for the development of new materials with specific properties, such as optical, electronic, or mechanical characteristics.
Used in Coordination Chemistry:
Oxazole,2-[(1S)-7'-[bis[3,5-bis(1,1-dimethylethyl)phenyl]phosphino]-2,2',3,3'-tetrahydro-1,1'-spirobi[1H-inden]-7-yl]-4,5-dihydrocan serve as a ligand in coordination chemistry, forming metal complexes with potential applications in catalysis, sensing, or as functional materials.
Used in Pharmaceutical Industry:
Oxazole,2-[(1S)-7'-[bis[3,5-bis(1,1-dimethylethyl)phenyl]phosphino]-2,2',3,3'-tetrahydro-1,1'-spirobi[1H-inden]-7-yl]-4,5-dihydrocan be utilized in the design and synthesis of new pharmaceutical compounds, taking advantage of its unique structural features and chiral nature for the development of novel drugs with improved efficacy and selectivity.
Used in Agrochemical Industry:
The complex structure and potential catalytic properties of Oxazole,2-[(1S)-7'-[bis[3,5-bis(1,1-dimethylethyl)phenyl]phosphino]-2,2',3,3'-tetrahydro-1,1'-spirobi[1H-inden]-7-yl]-4,5-dihydrocan be applied in the development of new agrochemicals, such as pesticides or herbicides, with enhanced performance and selectivity.

Relevant academic research and scientific papers

SPIRO PHOSPHORUS-OXAZOLINE, SYNTHESIS AND USE THEREOF

The present invention belongs to a spiro phosphine-oxazoline and preparation method and application thereof, particularly, publishes a novel spiro phosphine-oxazoline and the preparation method of its iridium complex. The substituted 7-diaryl phosphino-7'-carboxy-1,1'-Lo-dihydro-indene is used as the starting raw material to synthesize the novel spiro phosphine-oxazoline of the present invention through a two-step reaction. The novel spiro phosphine-oxazoline and the iridium precursor are complexed to become a complex, and then through ion exchange, an iridium/phosphine spiro-oxazoline complex with different anions can be obtained. The present invention overcomes the shortcomings of the existing technology. The cheap readily available amino alcohol is used as the raw material to synthesize the novel spiro phosphine-oxazoline, on the fourth position of the oxazoline ring of which there is no substituent. The iridium complex of this novel spiro phosphine-oxazoline can catalyze the asymmetric hydrogenation of α-substituted acrylic acid, and shows very high activity and enantioselectivity, therefore has a vey high research value and an industrialization prospect.

Iridium-catalyzed enantioselective hydrogenation of α,β- unsaturated carboxylic acids

A highly efficient iridium-catalyzed hydrogenation of α,β-unsaturated carboxylic acids has been developed by using chiral spiro-phosphino-oxazoline ligands, affording α-substituted chiral carboxylic acids in exceptionally high enantioselectivities and reactivities. Copyright