1040377-18-1

Basic information

• Product Name: 1H-Pyrazole-1-ethanol, β,β-diMethyl-4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl-
• Synonyms: 1H-Pyrazole-1-ethanol, β,β-diMethyl-4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl-;2-methyl-2-[4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]propan-1-ol;2-Methyl-2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)propan-1-ol;1H-Pyrazole-1-ethanol, beta,beta-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl-;2-Methyl-2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazol-1-yl]propan-1-ol;(1-(1-HYDROXY-2-METHYLPROPAN-2-YL)-1H-PYRAZOL-4-YL)BORONIC ACID PINACOL ESTER
• CAS NO: 1040377-18-1
• Molecular Formula: C₁₃H₂₃BN₂O₃
• Molecular Weight: 266.15
• Mol File: 1040377-18-1.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 392.0±22.0 °C(Predicted)
• Appearance: /
• Density: 1.07±0.1 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 14.33±0.10(Predicted)
• CAS DataBase Reference: 1H-Pyrazole-1-ethanol, β,β-diMethyl-4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrazole-1-ethanol, β,β-diMethyl-4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl-(1040377-18-1)
• EPA Substance Registry System: 1H-Pyrazole-1-ethanol, β,β-diMethyl-4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl-(1040377-18-1)

Safety Data

• Hazardous Substances Data: 1040377-18-1(Hazardous Substances Data)

Usage

General Description

1H-Pyrazole-1-ethanol, β,β-diMethyl-4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl- is a chemical compound with a pyrazole ring and a boron-containing moiety. It has two methyl groups on the nitrogen atom of the pyrazole ring and a boron-containing group attached to the oxygen atom of the ethanol group. 1H-Pyrazole-1-ethanol, β,β-diMethyl-4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl- is often used as a reagent in organic synthesis, particularly in the formation of carbon-carbon and carbon-heteroatom bonds. Its boron-containing group makes it useful in Suzuki-Miyaura coupling reactions, where it can facilitate the formation of aryl-aryl or aryl-heteroaryl bonds. Additionally, its pyrazole ring makes it a potential candidate for pharmaceutical research due to the biological activity associated with this structural motif.

Upstream product

• 1201657-32-0 ethyl 2-methyl-2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)propanoate 
• 269410-08-4 pyrazole-4-boronic acid pinacol ester 
• 877401-11-1 2-(4-bromo-1H-pyrazol-1-yl)-2-methylpropan-1-ol 
• 73183-34-3 bis(pinacol)diborane 

Downstream Products

• 1040376-87-1 2-(4-{5-[1-(2,6-dichloro-3-fluoro-phenyl)-ethoxy]-6-methyl-pyridin-3-yl}-pyrazol-1-yl)-2-methyl-propan-1-ol 

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