1040406-13-0Relevant articles and documents
Synthesis and in vitro antimycobacterial activity of B-ring modified diaryl ether InhA inhibitors
am Ende, Christopher W.,Knudson, Susan E.,Liu, Nina,Childs, James,Sullivan, Todd J.,Boyne, Melissa,Xu, Hua,Gegina, Yelizaveta,Knudson, Dennis L.,Johnson, Francis,Peloquin, Charles A.,Slayden, Richard A.,Tonge, Peter J.
, p. 3029 - 3033 (2008/12/23)
Previous structure-based design studies resulted in the discovery of alkyl substituted diphenyl ether inhibitors of InhA, the enoyl reductase from Mycobacterium tuberculosis. Compounds such as 5-hexyl-2-phenoxyphenol 19 are nM inhibitors of InhA and inhib
