104047-30-5 Usage
General Description
Ethyl 4,7-Dihydroxyquinoline-3-carboxylate is a chemical compound with the molecular formula C15H13NO5. It is a derivative of quinoline and contains two hydroxy groups at the 4 and 7 positions of the quinoline ring, as well as an ethyl ester group attached to the carboxylic acid at the 3 position. Ethyl 4,7-Dihydroxyquinoline-3-carboxylate has potential applications in the field of medicinal chemistry, particularly in the development of new drugs with anti-inflammatory, antioxidant, or antimicrobial properties. Additionally, it may also have uses in the production of dyes and pigments due to its quinoline structure. Further research and testing are needed to fully understand the potential uses and properties of Ethyl 4,7-Dihydroxyquinoline-3-carboxylate.
Check Digit Verification of cas no
The CAS Registry Mumber 104047-30-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,4,0,4 and 7 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 104047-30:
(8*1)+(7*0)+(6*4)+(5*0)+(4*4)+(3*7)+(2*3)+(1*0)=75
75 % 10 = 5
So 104047-30-5 is a valid CAS Registry Number.
104047-30-5Relevant articles and documents
Lead optimization of 3-carboxyl-4(1 H)-quinolones to deliver orally bioavailable antimalarials
Zhang, Yiqun,Clark, Julie A.,Connelly, Michele C.,Zhu, Fangyi,Min, Jaeki,Guiguemde, W. Armand,Pradhan, Anupam,Iyer, Lalitha,Furimsky, Anna,Gow, Jason,Parman, Toufan,El Mazouni, Farah,Phillips, Margaret A.,Kyle, Dennis E.,Mirsalis, Jon,Guy, R. Kiplin
, p. 4205 - 4219 (2012/07/02)
Malaria is a protozoal parasitic disease that is widespread in tropical and subtropical regions of Africa, Asia, and the Americas and causes more than 800,000 deaths per year. The continuing emergence of multidrug-resistant Plasmodium falciparum drives the ongoing need for the development of new and effective antimalarial drugs. Our previous work has explored the preliminary structural optimization of 4(1H)-quinolone ester derivatives, a new series of antimalarials related to the endochins. Herein, we report the lead optimization of 4(1H)-quinolones with a focus on improving both antimalarial potency and bioavailability. These studies led to the development of orally efficacious antimalarials including quinolone analogue 20g, a promising candidate for further optimization.