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2,2,2-trifluoro-1-[2-(3-trifluoro methyl-pyrazol-1-yl)-phenyl]-ethanol is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1040531-43-8 Structure
  • Basic information

    1. Product Name: 2,2,2-trifluoro-1-[2-(3-trifluoro methyl-pyrazol-1-yl)-phenyl]-ethanol
    2. Synonyms: 2,2,2-trifluoro-1-[2-(3-trifluoro methyl-pyrazol-1-yl)-phenyl]-ethanol
    3. CAS NO:1040531-43-8
    4. Molecular Formula:
    5. Molecular Weight: 310.199
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1040531-43-8.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 2,2,2-trifluoro-1-[2-(3-trifluoro methyl-pyrazol-1-yl)-phenyl]-ethanol(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2,2,2-trifluoro-1-[2-(3-trifluoro methyl-pyrazol-1-yl)-phenyl]-ethanol(1040531-43-8)
    11. EPA Substance Registry System: 2,2,2-trifluoro-1-[2-(3-trifluoro methyl-pyrazol-1-yl)-phenyl]-ethanol(1040531-43-8)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1040531-43-8(Hazardous Substances Data)

1040531-43-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1040531-43-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,4,0,5,3 and 1 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1040531-43:
(9*1)+(8*0)+(7*4)+(6*0)+(5*5)+(4*3)+(3*1)+(2*4)+(1*3)=88
88 % 10 = 8
So 1040531-43-8 is a valid CAS Registry Number.

1040531-43-8Relevant articles and documents

Modulation of peripheral serotonin levels by novel tryptophan hydroxylase inhibitors for the potential treatment of functional gastrointestinal disorders

Shi, Zhi-Cai,Devasagayaraj, Arokiasamy,Gu, Kunjian,Jin, Haihong,Marinelli, Brett,Samala, Lakshman,Scott, Sheldon,Stouch, Terry,Tunoori, Ashok,Wang, Ying,Zang, Yi,Zhang, Chengmin,Kimball, S. David,Main, Alan J.,Sun, Weimei,Yang, Qi,Nouraldeen, Amr,Yu, Xiang-Qing,Buxton, Eric,Patel, Shiv,Nguyen, Nghi,Swaffield, Jon,Powell, David R.,Wilson, Alan,Liu, Qingyun

supporting information; experimental part, p. 3684 - 3687 (2009/04/06)

The discovery of a novel class of peripheral tryptophan hydroxylase (TPH) inhibitors is described. This class of TPH inhibitors exhibits excellent potency in in vitro biochemical and cell-based assays, and it selectively reduces serotonin levels in the murine intestine after oral administration without affecting levels in the brain. These TPH1 inhibitors may provide novel treatments for gastrointestinal disorders associated with dysregulation of the serotonergic system, such as chemotherapy-induced emesis and irritable bowel syndrome.

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