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Usage

Uses

Used in Pharmaceutical Industry:
3-Amino-5-nitrobenzonitrile is used as a chemical intermediate for the synthesis of various pharmaceuticals. Its unique structure allows it to be a key component in the creation of drugs that target specific medical conditions.
Used in Agrochemical Industry:
In the agrochemical sector, 3-Amino-5-nitrobenzonitrile serves as an intermediate in the production of agrochemicals. It contributes to the development of pesticides and other agricultural products designed to improve crop yields and protect plants from pests.

Upstream product

• 4110-35-4 3,5-dinitrobenzonitrile 

Downstream Products

• 1220631-34-4 N-(3-cyano-5-nitrophenyl)-N-(methylsulfonyl)methanesulfonamide 
• 49674-34-2 3-cyano-5-nitrobenzene-1-sulfonyl chloride 

Relevant academic research and scientific papers

A Convenient, Efficient, and Environmentally Benign Method for Preparing Nitroanilines

An efficient method for the catalytic monoreduction of aromatic dinitro compounds to nitroanilines is reported. In the presence of selenium catalyst, the dinitroaromatic compounds are selectively reduced by CO/H2O to the corresponding nitroanilines under atmospheric pressure. The mono-reduction occurs in high selectivity regardless of the substitution groups on the aromatic ring without affecting other reducible functional groups.

Gold supported on titania for specific monohydrogenation of dinitroaromatics in the liquid phase

Liquid-phase selective monohydrogenation of various substituted dinitroaromatics to the corresponding valuable nitroanilines was investigated on gold-based catalysts. Special attention was paid to the effect of Au particle size on this monoreduction reaction. Interestingly, TiO2 supported gold catalysts containing a relatively larger mean Au particle size (>5 nm) showed far superior chemoselectivity for specific mono-hydrogenation of dinitroaromatics, with the highest performance attainable for the catalyst bearing Au particles of ca. 7.5 nm. Results in the intermolecular competitive hydrogenation showed that the intrinsic higher accumulation rates of the desired nitroanilines associated with the catalyst possessing larger Au particles were responsible for the high chemoselectivity observed. the Partner Organisations 2014.

IMIDAZOPYRIDAZINECARBONITRILES USEFUL AS KINASE INHIBITORS

The invention provides compounds of Formula (I) and pharmaceutically acceptable salts thereof. The Formula (I) imidazopyridazines inhibit protein kinase activity thereby making them useful as anticancer agents.

NOVEL AMIDE COMPOUNDS

A compound of the formula (I):R1-A-X-NHCO-Y-R2 ???whereinR1 is heterocyclic group which may have suitable substituents, or phenyl which may have suitable substituents,R2 is condensed phenyl which may have suitable substituents, phenyl which may have suitable substituents, or thienyl which may have suitable substituents,A is a group of the formula:-(CH2)t-(O)m- or in which R3 and R4 are each hydrogen or linked together to form imino,R5 is hydrogen or lower alkyl,t is 0, 1 or 2,p, m and n are each 0 or 1,X is phenylene which may have suitable substituents, or bivalent heterocyclic group containing nitrogen which may have suitable substituents,Y is bond, lower alkylene, or lower alkenylene, and a salt thereof.

Antisecretory oxamic acid esters

Variously substituted oxanilic acid esters possessing anti-secretory activity are useful anti-ulcer agents.

Antisecretory oxamic acid esters

Variously substituted oxanilic acid esters possessing anti-secretary activity are useful anti-ulcer agents.