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1040724-41-1

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1040724-41-1 Usage

General Description

5-(4-chloro-2-methylphenyl)-1H-Pyrazol-3-amine is a chemical compound with the molecular formula C10H9ClN4. It is a pyrazole derivative, which is a class of organic compounds that contain a five-membered heterocyclic ring structure. This specific compound is characterized by the presence of a 4-chloro-2-methylphenyl group attached to the pyrazole ring, as well as an amine functional group. It has potential applications in the field of pharmaceuticals and agrochemicals, as pyrazole derivatives have been studied for their various biological activities, including antimicrobial, antioxidant, and anti-inflammatory properties. The compound may also have industrial uses in the synthesis of other organic compounds. Proper handling and storage of this chemical are important to ensure safety and prevent any potential hazards associated with its use.

Check Digit Verification of cas no

The CAS Registry Mumber 1040724-41-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,4,0,7,2 and 4 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1040724-41:
(9*1)+(8*0)+(7*4)+(6*0)+(5*7)+(4*2)+(3*4)+(2*4)+(1*1)=101
101 % 10 = 1
So 1040724-41-1 is a valid CAS Registry Number.

1040724-41-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-(4-chloro-2-methylphenyl)-2H-pyrazol-3-ylamine

1.2 Other means of identification

Product number -
Other names 5-(4-chloro-2-methyl-phenyl)-2H-pyrazol-3-ylamine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1040724-41-1 SDS

1040724-41-1Relevant articles and documents

Design and synthesis of a hybrid series of potent and selective agonists of α7 nicotinic acetylcholine receptor

Nencini, Arianna,Castaldo, Cristiana,Comery, Thomas A.,Dunlop, John,Genesio, Eva,Ghiron, Chiara,Haydar, Simon,Maccari, Laura,Micco, Iolanda,Turlizzi, Elisa,Zanaletti, Riccardo,Zhang, Jean

, p. 401 - 418 (2014/04/17)

α7 nicotinic acetylcholine receptor agonists are promising therapeutic candidates for the treatment of cognitive impairment. As a follow up of our internal medicinal chemistry program we investigated a novel series of α7 nAChR agonists. Starting from molecular docking studies on two series of molecules recently developed in our laboratories, an alternative scaffold was designed attempting to combine the optimal features of these previously identified urea and pyrazole compounds. Based on our previous SAR knowledge and on predicted drug-like properties, a small library was synthesized in parallel manner, affording compounds with excellent α7 nAChR activity, selectivity and preliminary ADME profile.

NICOTINIC ACETYLCHOLINE RECEPTOR MODULATORS

-

Page/Page column 62, (2008/12/07)

The present invention provides compounds of formula (I) and compositions thereof, methods of making them, and methods of using them to modulate alpha7 nicotinic acetylcholine receptors and/or to treat any of a variety of disorders, diseases, and conditions. Provided compounds can affect, among other things, neurological, psychiatric and/or inflammatory system.

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