1040833-70-2Relevant academic research and scientific papers
Total syntheses of (+)- and (-)-pestalotiopsin A
Takao, Ken-Ichi,Hayakawa, Nobuhiko,Yamada, Reo,Yamaguchi, Taro,Saegusa, Hiroshi,Uchida, Masatoshi,Samejima, Suguru,Tadano, Kin-Ichi
supporting information; experimental part, p. 6452 - 6461 (2009/12/24)
(Chemical Equation Presented) An enantioselective total synthesis of both enantiomers of caryophyllene-type sesquiterpenoid pestalotiopsin A has been achieved, thereby establishing the absolute stereochemistry of natural (+)-pestalotiopsin A. Highlights o
Total synthesis of (-)-pestalotiopsin A
Takao, Ken-Ichi,Hayakawa, Nobuhiko,Yamada, Reo,Yamaguchi, Taro,Morita, Urara,Kawasaki, Soujiro,Tadano, Kin-Ichi
, p. 3426 - 3429 (2008/12/23)
(Chemical Equation Presented) A big + : The total synthesis of (-)-pestalotiopsin A has been achieved, thereby establishing the absolute stereochemistry of natural (+)-pestalotiopsin A (see scheme). The synthesis features a [2+2] cycloaddition, an aldol reaction, and an intramolecular Nozaki-Hiyama-Kishi reaction to construct the (E)-cyclononene ring.
