1040919-30-9

Upstream product

• 1192489-59-0 2-(dichloromethyl)-N-[(1R)-1-phenylethyl]-cyclopent-3-ene-1-carboxamide 
• 1192489-62-5 (3aR,6aS,3a'R,6a'S)-3,3'-oxybis{2-[(1R)-1-phenylethyl]-3,3a,6,6a-tetrahydrocyclopenta[c]pyrrol-1(2H)-one} 
• 1192489-59-0 2-(dichloromethyl)-N-[(1R)-1-phenylethyl]cyclopent-3-ene-1-carboxamide 
• 5307-99-3 (+/-)-7,7-dichlorobicyclo[3.2.0]hept-2-en-6-one 
• 3886-69-9 (R)-1-phenyl-ethyl-amine 

Downstream Products

• 1192489-62-5 (3aR,6aS,3a'R,6a'S)-3,3'-oxybis{2-[(1R)-1-phenylethyl]-3,3a,6,6a-tetrahydrocyclopenta[c]pyrrol-1(2H)-one} 
• 1040919-33-2 (1S,2R)-2-(hydroxymethyl)-N-[(1R)-phenylethyl]-cyclopent-3-ene-1-carboxamide 

Relevant academic research and scientific papers

Epoxy derivatives of {(5-[(1-Phenylethyl)aminocarbonyl]-cyclopent-2-en-1- yl}methyl acetates

Diastereoisomeric [(1R,5S)-5-"[(1R)-1-phenylethyl] aminocarbonyl"cyclopent-2-en-1-yl]methyl acetate and [(1S,5R)-5-"[(1R) -1-phenylethyl]aminocarbonyl"cyclopent-2-en-1-yl]methyl acetate reacted with m-chloroperoxybenzoic acid to give the corresponding ste

Features of catalyzed hydration of 2-(dichloromethyl)-N-[(1R)-1- phenylethyl)]cyclopent-3-ene-1-carboxamides

The hydration of gem-dichloromethyl group in 2-(dichloromethyl)-N-[(1R)-1- phenylethyl)]cyclopent-3-ene-1-carboxamides in aqueous acetonitrile catalyzed by AgNO3, FeCl3?6H2O, PdCl2, and BaO was investigated. The optimum results were obtained at the use of BaO. It was demonstrated, that Pd-catalyzed reactions initiated intermolecular ether formation from the primary hydration products, bicyclic amides.

Simple synthetic protocol for the preparation of enantiomeric 3-oxabicyclo[3.3.0]oct-6-en-2-ones

Diastereomeric amides produced via the decomposition of easily available (±)-7,7-dichlorobicyclo[3.2.0]hept-2-en-6-one by treatment with (+)- or (-)-α-methylbenzylamines were transformed into bicyclic lactam-aminals, which can easily be separated using the column chromatography on SiO2. The latter products lead to enantiomeric 3-oxabicyclo[3.3.0]oct-6-en-2-ones after the removal of the chiral auxiliary. Crown Copyright