1040923-97-4Relevant academic research and scientific papers
A new type of L-Tertiary leucine-derived ligand: Synthesis and application in Cu(II)-catalyzed asymmetric Henry reactions
Cai, Zedong,Lan, Ting,Ma, Pengfei,Zhang, Jingfang,Yang, Qingqing,He, Wei
supporting information, (2019/08/08)
A new series of Schiff bases derived from amino acids were developed as chiral ligands for Cu(II)-catalyzed asymmetric Henry reactions. The optimum ligand 7d exhibited outstanding catalytic efficiency in the Cu(II)-catalyzed asymmetric Henry additions of four nitroalkanes to different kinds of aldehydes to produce 76 desired adducts in high yields (up to 96%) with excellent enantioselectivities, up to 99% enantiomeric excess (ee).
Urea/transition-metal cooperative catalyst for anti-selective asymmetric nitroaldol reactions
Lang, Kai,Park, Jongwoo,Hong, Sukwon
supporting information; experimental part, p. 1620 - 1624 (2012/04/05)
A cooperative catalyst that features urea H-bonding and a cobalt center was developed for anti-selective asymmetric Henry reactions (see scheme). The H-bonds of urea play a crucial role in the improvement in yield (from 30 % to 84 %), enantioselectivity (
Asymmetric Henry reactions catalyzed by metal complexes of chiral boron-bridged bisoxazoline (borabox) ligands
Toussaint, Aurelie,Pfaltz, Andreas
scheme or table, p. 4591 - 4597 (2009/05/07)
Metal complexes of boron-bridged bisoxazolines (borabox ligands) were evaluated as catalysts for the Henry reaction. Copper(II) complexes induced high enantio- and diastereoselectivity in reactions with nitroethane and nitropropane. The amount of base add
New highly asymmetric henry reaction catalyzed by CuII and a C1-symmetric aminopyridine ligand, and its application to the synthesis of miconazole
Blay, Gonzalo,Domingo, Luis R.,Hernandez-Olmos, Victor,Pedro, Jose R.
supporting information; experimental part, p. 4725 - 4730 (2009/05/07)
A new catalytic asymmetric Henry reaction has been developed that uses a C1 -symmetric chiral aminopyridine ligand derived from camphor and picolylamine. A variety of aromatic, heteroaromatic, aliphatic, and unsaturated aldehydes react with nit
