1041143-13-8Relevant articles and documents
Intramolecular direct arylation in the synthesis of fluorinated carbazoles
Bedford, Robin B.,Betham, Michael,Charmant, Jonathan P.H.,Weeks, Amanda L.
, p. 6038 - 6050 (2008/12/20)
The amination of 2-chloroanilines with aryl bromides and subsequent intramolecular direct arylation can be exploited in the synthesis of a range of fluorinated carbazoles, where the fluorine substituent can be introduced via the aniline, the aryl bromide or both substrates. Depending on substitution patterns, the two steps can either be performed in tandem in one-pot under microwave heating conditions or else require a two pot approach.
