104115-76-6

Usage

Uses

Used in Pharmaceutical Industry:
3-Methoxynaphthalene-2-boronic acid is used as a key intermediate in the development of pharmaceutical agents and drug candidates, owing to its reactivity in Suzuki-Miyaura cross-coupling reactions, which facilitate the synthesis of complex organic molecules with potential therapeutic applications.
Used in Agrochemical Production:
In the agrochemical industry, 3-Methoxynaphthalene-2-boronic acid is utilized as a precursor for the synthesis of various agrochemicals, contributing to the development of effective pest control and crop protection products.
Used in Dye Synthesis:
3-Methoxynaphthalene-2-boronic acid is employed as a building block in the production of dyes, leveraging its structural and reactive properties to create dyes with specific color characteristics and applications in various industries.
Used in Chemistry Research:
3-Methoxynaphthalene-2-boronic acid is used as a research compound in chemistry, enabling scientists to explore its properties, reactivity, and potential applications in the synthesis of new materials and compounds.

Upstream product

• 121-43-7 Trimethyl borate 
• 93-04-9 2-Methoxynaphthalene 
• 3401-47-6 1-bromo-2-methoxynaphthalene 

Downstream Products

• 880252-12-0 2-(3-methoxy-naphthalen-2-yl)-benzoic acid methyl ester 
• 1256544-22-5 1-bromo-2-methoxy-3-(2-fluorophenyl)naphthalene 
• 1256544-23-6 1-bromo-2-hydroxy-3-(2-fluorophenyl)naphthalene 
• 1256544-21-4 2-methoxy-3-(2-fluorophenyl)naphthalene 
• 1256544-86-1 5-(3-bromophenyl)benzo[b]naphtho[2,3-d]furan 

Relevant academic research and scientific papers

Synthesis and properties of a new member of the calixnaphthalene family: A C2-Symmetrical endo-calix[4]naphthalene

The synthesis of a new endo-calix[4]naphthalene is described. The reaction sequence involves the cyclocondensation of a key bisnaphthylmethane intermediate (8) with formaldehyde. This key intermediate (8) is formed using a modified Suzuki-Miyaura Pd-catalyzed crosscoupling reaction between bromomethylnaphthyl (6) and naphthylboronic acid (7), both of which can be derived from 2-hydroxynaphthoic acid.

COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME

When a decrease in low-grey level region (e.g., 0 to 80 grey) efficiencies of organic light emitting devices is not constant, deviation among display panels may cause color change and stain in the low luminance region. Aspects of the present disclosure ar

ANTHRACENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE ELEMENT USING SAME

An anthracene derivative represented by the following formula (1): wherein in the formula (1), L1 is selected from a single bond and a linking group, and the linking group is selected from a divalent arylene group, a divalent heterocyclic group, and a group formed by linking of 2 to 4 of divalent arylene groups and/or divalent heterocyclic groups. Ar1 is selected from the following formulas (2) and (3). In the formulas (2) and (3), X is selected from an oxygen atom and a sulfur atom. In the formula (2), any one of R11 to R14 is used for bonding to L1. In the formula (3), any one of R21 to R24 is used for bonding to L1. Ar2 is selected from a substituted or unsubstituted aryl group including 6 to 50 ring carbon atoms and a substituted or unsubstituted heterocyclic group including 5 to 50 ring atoms.

Unexpected results of a SNAr-reaction. A novel synthetic approach to 1-arylthio-2-naphthols

1-(Phenylthio)-3-(pyridin-3-yl)-2-naphthol was obtained as an unexpected result of a nucleophilic aromatic substitution reaction of 3-(pyridine-3-yl) naphthalene-2-yl trifluoromethanesulfonate with thiophenol. This observation led to the discovery of an e

ANTHRACENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING THE SAME

An anthracene derivative represented by the following formula (1): In the formula (1), Z is a structure represented by the following formula (2). In the formula (2), at least one pair of adjacent two substituents of R11 to R18 form a ring represented by the following formula (3) or (4):

Novel aldosterone synthase inhibitors with extended carbocyclic skeleton by a combined ligand-based and structure-based drug design approach

Pharmacophore modeling of a series of aldosterone synthase (CYP11B2) inhibitors triggered the design of compounds 11 and 12 by extending a previously established naphthalene molecular scaffold (e.g., present in molecules 1 and 2) via introduction of a phenyl or benzyl residue in 3-position. These additional aromatic moieties have been hypothesized to fit into the newly identified hydrophobic pharmacophore feature HY3. Subsequent docking studies in our refined CYP11B2 protein model have been performed prior to synthesis to estimate the inhibitory properties of the proposed molecules. While phenyl-substituted compound 11 (IC50 > 500 nM) did not dock under the given pharmacophore constraint (i.e., the Fe(heme)-N(ligand) interaction), benzyl-substituted compound 12 (IC50 = 154 nM) was found to exploit a previously unexplored subpocket of the inhibitor binding site. By structural optimization based on the pharmacophore hypothesis, 25 novel compounds were synthesized, among them highly potent CYP11B2 inhibitors (e.g., 17, IC 50 = 2.7 nM) with pronounced selectivity toward the most important steroidogenic and hepatic CYP enzymes.

FUSED HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE

To provide a material for an organic light emitting device showing a light emission hue with an extremely good purity and outputting light having high luminance and a long lifetime with high efficiency, the present invention relates to a fused heterocycli

Synthesis and biological evaluation of novel naphthocarbazoles as potential anticancer agents

We report the efficient synthesis involving palladium-catalyzed reactions and biological evaluation of new naphthocarbazoles designed as potential anticancer agents. The use of 5- and 6-benzyloxyindoles generated three substitution sites which were succes

Synthesis and photochromic properties of 2H,9H-indeno[1,2-f]- and 3H,7H-indeno[2,1-i]-naphtho[2,1-b]pyrans

Expedient syntheses of the 3-hydroxy- and 6-hydroxy- derivatives of 11H-benzo[a]-fluoren-11-one, obtained via Suzuki-Miyaura couplings are described. Reactions of these phenols with 1,1-diarylprop-2-yn-1-ols give indeno[2,1-i]- and indeno[1,2-f]-naphtho[2