1041173-22-1Relevant articles and documents
Synthesis of enantiopure 1,4-dioxanes, morpholines, and piperazines from the reaction of chiral 1,2-diols, amino alcohols, and diamines with vinyl selenones
Bagnoli, Luana,Scarponi, Catalina,Rossi, Maria Giovanna,Testaferri, Lorenzo,Tiecco, Marcello
, p. 993 - 999 (2011/03/20)
The reactions of readily available vinyl selenones with enantiopure 1,2-diols, N-protected-1,2-aminoalcohols, and diamines gave substituted enantiopure 1,4-dioxanes, morpholines, and piperazines, respectively, in good to excellent yields. The same procedu
An annulation reaction for the synthesis of morpholines, thiomorpholines, and piperazines from β-heteroatom amino compounds and vinyl sulfonium salts
Yar, Muhammad,McGarrigle, Eoghan M.,Aggarwal, Varinder K.
, p. 3784 - 3786 (2008/12/23)
(Chemical Equation Presented) Heterocycling: Diphenyl vinyl sulfonium salt 1 acts first as an electrophile, then a base, and then again as an electrophile in this operationally simple, high yielding, one-pot synthesis of pharmacologically important morpholines, thiomorpholines, and piperazines. Compound 1 is an excellent synthon for the 1,2-ethane dication.