1041421-83-3

Basic information

• Product Name: C₁₄H₁₁ClN₃O₂^(1-)*Na⁽¹⁺⁾
• CAS NO: 1041421-83-3
• Molecular Weight: 311.703
• Mol File: 1041421-83-3.mol

Chemical Properties

• CAS DataBase Reference: C₁₄H₁₁ClN₃O₂^(1-)*Na⁽¹⁺⁾(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₄H₁₁ClN₃O₂^(1-)*Na⁽¹⁺⁾(1041421-83-3)
• EPA Substance Registry System: C₁₄H₁₁ClN₃O₂^(1-)*Na⁽¹⁺⁾(1041421-83-3)

Safety Data

• Hazardous Substances Data: 1041421-83-3(Hazardous Substances Data)

Upstream product

• 1041422-09-6 C₁₅H₁₄ClN₃O₂ 

Relevant articles and documents

The discovery of fused pyrrole carboxylic acids as novel, potent d-amino acid oxidase (DAO) inhibitors

The 'NMDA hypofunction hypothesis of schizophrenia' can be tested in a number of ways. DAO is the enzyme primarily responsible for the metabolism of d-serine, a co-agonist for the NMDA receptor. We identified novel DAO inhibitors, in particular, acid 1, which demonstrated moderate potency for DAO in vitro and ex vivo, and raised plasma d-serine levels after dosing ip to rats. In parallel, analogues were prepared to survey the SARs of 1.