1041448-72-9Relevant academic research and scientific papers
The stereochemistry of 1,3-dipolar cycloaddition of internally H-bonded chiral methylenenitrones
Ali, Shaikh A.,Iman, Muhammad Z.N.
, p. 9134 - 9145 (2007)
A study of diastereoselectivity in the cycloaddition reactions of a series of mono- and disubstituted alkenes with two chiral, internally H-bonded methylenenitrones has been carried out. The high degree of stereochemical control in the presence of anhydro
The regio- and stereo-chemistry of 1,3-dipolar cycloaddition of a chiral methylenenitrone to 1,2-disubstituted alkenes
Ali, Shaikh A.,Iman, Muhammad Z.N.
, p. 38 - 47 (2008/12/21)
A study of regio- and stereo-selectivity in the cycloaddition reactions of a series of symmetrical and unsymmetrical 1,2-disubstituted alkenestothechiral, internally H-bonded N-(2-hydroxy-1-phenyl)methylenenitrone, has been carried out. The regioselectivity observed in the addition reactions is explained in terms of frontier orbital interactions. The alkenes having a hydroxymethyl substituent at the allylic position are found to undergo regio- as well as highly stereo-selective cycloaddition reactions in the presence of anhydrous magnesium bromide.
