1041672-48-3Relevant academic research and scientific papers
Rapid stereoselective access to the tetracyclic core of puupehenone and related sponge metabolites using metal-free radical cyclisations of cyclohexenyl-substituted 3-bromochroman-4-ones
Pritchard, Robin G.,Sheldrake, Helen M.,Taylor, Isobel Z.,Wallace, Timothy W.
, p. 4156 - 4159 (2008/09/20)
The tetracyclic nucleus of puupehenone, 15-oxopuupehenol and other sesquiterpene-phenol natural products can be assembled stereoselectively in three steps, the last of these being the 6-endo-trig cyclisation of an alpha-keto radical generated from a substituted 2-(2-cyclohexenyl)ethyl 3-bromo-4-chromanone under metal-free conditions.
