104174-63-2Relevant academic research and scientific papers
Sequential Birch reaction and asymmetric Ir-catalyzed hydrogenation as a route to chiral building blocks
Paptchikhine, Alexander,Itto, Kaori,Andersson, Pher G.
supporting information; experimental part, p. 3989 - 3991 (2011/06/09)
A range of 1,2,4-trisubstituted cyclohexadienes obtained from the Birch reaction were hydrogenated asymmetrically to produce synthetically valuable chiral compounds in high enantio- and diastereoselectivity. The Royal Society of Chemistry.
2-AMINO- AND 2-THIO-SUBSTITUTED 1,3-DIAMINOPROPANES
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Page/Page column 193, (2008/06/13)
Disclosed are compounds of the formula: where variables Q, Z, X, R15, R2, R3, and Rc are defined herein. Compounds disclosed herein are inhibitors of the beta-secretase enzyme and are therefore useful in the treatment of Alzheimer’s disease and other diseases characterized by deposition of A beta peptide in a mammal.
