104183-45-1

Basic information

• Product Name: (5Z)-5-(phenylmethylidene)-3-[({4-[(4-phenylpiperazin-1-yl)carbonyl]phenyl}amino)methyl]-2-thioxo-1,3-thiazolidin-4-one
• Synonyms: 5-Benzylidene-3-(p-(4-phenylpiperazin-1-ylcarbonyl)anilinomethyl)-4-oxothiazolidine-2-thione; Piperazine, 1-(4-(((4-oxo-5-(phenylmethylene)-2-thioxo-3-thiazolidinyl)methyl)amino)benzoyl)-4-phenyl-
• CAS NO: 104183-45-1
• Molecular Formula: C₂₈H₂₆N₄O₂S₂
• Molecular Weight: 514.6616
• Mol File: 104183-45-1.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 741.6°C at 760 mmHg
• Flash Point: 402.3°C
• Density: 1.4g/cm³
• Vapor Pressure: 7.31E-22mmHg at 25°C
• Refractive Index: 1.746
• CAS DataBase Reference: (5Z)-5-(phenylmethylidene)-3-[({4-[(4-phenylpiperazin-1-yl)carbonyl]phenyl}amino)methyl]-2-thioxo-1,3-thiazolidin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: (5Z)-5-(phenylmethylidene)-3-[({4-[(4-phenylpiperazin-1-yl)carbonyl]phenyl}amino)methyl]-2-thioxo-1,3-thiazolidin-4-one(104183-45-1)
• EPA Substance Registry System: (5Z)-5-(phenylmethylidene)-3-[({4-[(4-phenylpiperazin-1-yl)carbonyl]phenyl}amino)methyl]-2-thioxo-1,3-thiazolidin-4-one(104183-45-1)

Safety Data

• Hazardous Substances Data: 104183-45-1(Hazardous Substances Data)

Upstream product

• 50-00-0 formaldehyd 
• 3806-42-6 5-benzylidene-2-thioxothiazolidin-4-one 
• 79834-39-2 p-(4-Phenylpiperazin-1-ylcarbamoyl)aniline 

Relevant articles and documents

Synthesis and Biodynamic Activities of 5-(Substituted benzylidene)-3--4-oxothiazolidine-2-thiones

Twenty three title compounds (Va-w) have been synthesised by the Mannich Reaction between 5-arylidene-4-oxothiazolidine-2-thiones (II) and p-(N,N-disubstituted carbamoyl)anilines (IV) and screened for their antibacterial activity against B. cereus, S. aureus, M. flavus, S. lutae and B. subtilis, antiviral activity against Tobacco Mosaic Virus and CNS activities on albino mice.Some of the compounds give interesting results.Structure activity relationship has also been studied.