1041850-07-0Relevant academic research and scientific papers
Synthesis of tetrasubstituted NH pyrroles and polysubstituted furans via an addition and cyclization strategy
Li, Liang,Zhao, Mi-Na,Ren, Zhi-Hui,Li, Jianli,Guan, Zheng-Hui
experimental part, p. 532 - 540 (2012/04/04)
The FeCl3-catalyzed addition and cyclization of enamino esters with nitroolefins provides a straightforward and general method for the synthesis of tetrasubstituted NH pyrroles. This novel method tolerates a wide range of functionality, and allows for rapid elaboration of the nitroolefins into a variety of substituted pyrroles in good yields. Further, an efficient KOAc-promoted addition and cyclization protocol toward substituted furans has been described as well. Georg Thieme Verlag Stuttgart · New York.
Synthesis of tetrasubstituted furans via In-catalyzed propargylation of 1,3-dicarbonyl compounds-cyclization tandem process
Feng, Xunbo,Tan, Ze,Chen, De,Shen, Youming,Guo, Can-Cheng,Xiang, Jiannan,Zhu, Chengliang
, p. 4110 - 4112 (2008/09/21)
An efficient method to synthesize tetrasubstituted furans using simple starting materials such as propargylic alcohols and 1,3-dicarbonyl compounds has been developed. It was discovered that InCl3 could catalyze this transformation efficiently
