1041863-26-6Relevant articles and documents
Straightforward access to protected syn α-amino-β-hydroxy acid derivatives
Patel, Jignesh,Clave, Guillaume,Renard, Pierre-Yves,Franck, Xavier
, p. 4224 - 4227 (2008)
(Chemical Equation Presented) Titanium stability: syn α-Amino-β- hydroxy acid derivatives were prepared in excellent diastereoselectivities by an aldol reaction with chiral N-(azidoacetyl)thiazolidin-2-thione derivatives (see scheme; NMP = N-methylpyrrolidinone). Titanium enolates of these derivatives are stable and provide a new and efficient method to access chiral amino acids.