1042-59-7

Basic information

• Product Name: 20-methylpregn-5-en-3 beta-ol
• Synonyms: 20-methylpregn-5-en-3 beta-ol
• CAS NO: 1042-59-7
• Molecular Formula: C22H36 O
• Molecular Weight: 0
• Mol File: 1042-59-7.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 418.6°Cat760mmHg
• Flash Point: 178.1°C
• Appearance: /
• Density: 1.02g/cm³
• Vapor Pressure: 9.28E-09mmHg at 25°C
• Refractive Index: 1.537
• CAS DataBase Reference: 20-methylpregn-5-en-3 beta-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 20-methylpregn-5-en-3 beta-ol(1042-59-7)
• EPA Substance Registry System: 20-methylpregn-5-en-3 beta-ol(1042-59-7)

Safety Data

• Hazardous Substances Data: 1042-59-7(Hazardous Substances Data)

Usage

Commonly known as

20M5P

Type

Synthetic hormone

Used in

Production of progestogens

Derivative of

Progesterone

Chemical structure

Similar to progesterone with a methyl group added at the 20th carbon position

Activity

Demonstrated progestogenic activity

Application

Used in pharmaceutical industry for synthesis of progestin drugs

Role

Key in development of hormone replacement therapies and contraceptives

Also used in

Treatment of gynecological disorders

Nature

Synthetic

Allows for

Precise control over properties

Valuable tool in

Development of new medical treatments

InChI:InChI=1/C22H36O/c1-14(2)18-7-8-19-17-6-5-15-13-16(23)9-11-21(15,3)20(17)10-12-22(18,19)4/h5,14,16-20,23H,6-13H2,1-4H3/t16-,17-,18+,19-,20-,21-,22+/m0/s1

Upstream product

• 33168-84-2 3β-acetoxy-20-methylpregn-5-ene 
• 1474-14-2 (R)-2-((8S,9S,10R,13S,14S,17R)-3-Acetoxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-propionic acid 
• 1474-14-2 (S)-2-((8S,9S,10R,13S,14S,17R)-3-Acetoxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-propionic acid 
• 55509-37-0 Acetic acid (8S,9S,10R,13S,14S,17R)-17-((R)-2-hydroxy-1-methyl-ethyl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl ester 
• 55509-37-0 Acetic acid (8S,9S,10R,13S,14S,17R)-17-((S)-2-hydroxy-1-methyl-ethyl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl ester 
• 10211-88-8 (20S)-3β-acetoxybisnorchol-5-en-22-al 
• 74996-92-2 3β-acetoxy-21-chlorobisnorchol-5-ene 
• 74996-92-2 3β-acetoxy-22-chlorobisnorchol-5-ene 
• 103034-73-7 3β-hydroxy-23,24-dinor-chol-5-en-22-oic acid ethyl ester 
• 38388-16-8 (8S,9S,10R,13S,14S,17R)-10,13-dimethyl-17-(prop-1-en-2-yl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl acetate 
• 64070-60-6 3β-acetoxy-20-methylpregn-5-ene-20-ol 
• 102701-81-5 3β-Chlor-20-methyl-5-pregnen 
• 1474-14-2 3β-acetoxybisnor-5-cholenic acid 
• 10162-98-8 (20S)-20-methyl-pregnene-(5)-diol-(3β.21) 

Downstream Products

• 102848-92-0 20-Methyl-5α-pregnan-3-on 
• 5737-19-9 20-Methyl-5α-pregnan 
• 38388-19-1 20-Methylpregn-4-en-3-on 

Relevant articles and documents

Short side chain sterols from the tunicate Polizoa opuntia

The sterol composition of the Patagonian tunicate Polizoa opuntia was examined, and twenty-four compounds were identified as having either a Δ5, Δ7 or Δ0 nucleus. Two of them, the rare 20-methylpregn-5-en-3β-ol and 20-ethylpregn-5-en-3β-ol, were previously unreported as natural products from tunicates. These compounds were present only as trace components: therefore, their structures were confirmed by synthesis from suitable precursors and by comparison of the spectral and chromatographic constants of the synthetic and natural compounds.

Studies on steroids LXIII. Synthesis of cholesterol analogs with a modified side chain

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