104202-49-5

Upstream product

• 121-33-5 vanillin 
• 244771-18-4 Formic acid 3-methoxy-4-methoxymethoxy-phenyl ester 
• 5533-00-6 3-methoxy-4-methoxymethoxy-benzaldehyde 

Downstream Products

• 104202-36-0 1,3-dimethoxy-4-methoxymethoxybenzene 
• 2880-58-2 2-methoxy-1,4-benzoquinone 
• 244770-97-6 4-tert-Butyldimethylsilyloxy-2-methoxy-1-methoxymethoxy-6-pentylbenzene 
• 15121-94-5 primine 
• 244770-96-5 4-tert-Butyldimethylsilyloxy-2-methoxy-1-methoxymethoxybenzene 

Relevant academic research and scientific papers

New syntheses of the benzoquinone primin and its water-soluble analog primin acid via Heck reactions

The syntheses of primin, 2-methoxy-6-pentylbenzoquinone (1), a major allergen of Primula obconica, and its water-soluble acid analog primin acid (2) are reported. The key steps were ortho-lithiation reactions of protected hydroquinones, palladium coupling (Heck) reactions, and salcomine-catalyzed oxidations of phenols to quinones.

Phenol compound having antioxidative activity and the process for preparing the same

Disclosed are a phenol compound represented by the formula (1): STR1 wherein R0 represents H, alkyl or alkyloxy; R1 represents alkyl; R2 represents alkyl or alkyloxy; OR3 represents OH; R4 represents H, lower alkyl or acyl, each of the above substituents may be substituted; W represents O, S or NR7 ; where R7 represents H, alkyl, aryl, OH or alkyloxy, a group of the formula (2): STR2 represents an amino which may be mono- or di-substituted or heterocyclic group containing N atom, or a pharmaceutically acceptable salt thereof, and a process for preparing the same.

The Baeyer-Villiger Oxidation of Aromatic Aldehydes and Ketones with Hydrogen Peroxide Catalyzed by Selenium Compounds

A series of organoselenium compounds was investigated as activators of hydrogen peroxide in the Baeyer-Villiger oxidation.As a result, a convenient and cheap method for transformation of aromatic aldehydes, having polycondensed ring systems or electron-donating substituents, and polymethoxy derivatives of acetophenone, into phenols was elaborated.This method utilizes hydrogen peroxide activated by areneseleninic acids, as oxidizing agent.

An Improved Synthesis of 1,4-Benzo- and 1,4-Naphthoquinones Bearing Active Substituents

The synthesis of 1,4-benzoquinones and 1,4-naphthoquinones 3a-j carrying substituents such as methoxyl, allyl or oxiranyl was substantially improved.The 1-methoxy-4-methoxymethyloxy 2a-d, g-k or 1,4-bis(methoxymethyloxy) derivatives 2e-f were used, as a substrates instead of 1,4-dimethoxy derivatives 1a-j hitherto used and they were oxidized with silver(II) dipicolinate.Among numerous examples, the synthesis of a new analog of ubiquinone 3d with the oxiranyl substituent, being a new bioactivated alkylating agent, is reported.