104210-91-5

Upstream product

• 18162-48-6 tert-butyldimethylsilyl chloride 
• 122-57-6 1-Phenylbut-1-en-3-one 
• 1896-62-4 (E)-benzalacetone 
• 69739-34-0 t-butyldimethylsiyl triflate 

Downstream Products

• 134593-95-6 6-<(tert-butyldimethylsilyl)oxy>-3-methyl-8-phenyl-4a,5,8,8a-tetrahydro-1H-benzopyran-1-one 
• 134594-03-9 9-<(tert-butyldimethylsilyl)oxy>-6a-(methoxycarbonyl)-7-phenyl-6a,7,10,10a-tetrahydro-6H-dibenzopyran-6-one 
• 134594-02-8 9-<(tert-butyldimethylsilyl)oxy>-6a-(ethoxycarbonyl)-7-phenyl-6a,7,10,10a-tetrahydro-6H-dibenzopyran-6-one 
• 134594-09-5 9-<(tert-butyldimethylsilyl)oxy>-6a-(ethoxycarbonyl)-7-phenyl-6a,7,10,10a,11,12-hexahydro-6H-benzonaphtho<1,2-b>pyran-6-one 
• 126713-52-8 10-Benzo[1,3]dioxol-5-yl-8-(tert-butyl-dimethyl-silanyloxy)-2-phenyl-3-oxa-1-aza-spiro[4.5]deca-1,7-dien-4-one 
• 120019-59-2 1-[(1S,2S,6S)-4-(tert-Butyl-dimethyl-silanyloxy)-6-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2-phenyl-cyclohex-3-enyl]-ethanone 
• 119927-78-5 1-[(1R,2R,6R)-4-(tert-Butyl-dimethyl-silanyloxy)-6-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2-phenyl-cyclohex-3-enyl]-ethanone 
• 130043-08-2 (6aS,7S,10aS)-9-(tert-Butyl-dimethyl-silanyloxy)-7-phenyl-6a,7,10,10a-tetrahydro-benzo[c]chromen-6-one 
• 134593-97-8 9-<(tert-butyldimethylsilyl)oxy>-7-phenyl-6a,7,10,10a-tetrahydro-6H-dibenzopyran-6-one 
• 167401-58-3 1-t-butyldimethylsiloxy-1-(2-phenylethenyl)cyclopropane 

Relevant academic research and scientific papers

Highly-functionalized arene synthesis based on palladium on carbon-catalyzed aqueous dehydrogenation of cyclohexadienes and cyclohexenes

Transition metal-catalyzed dehydrogenation is a clean oxidation method requiring no additional oxidants. We have accomplished a heterogeneous Pd/C-catalyzed aqueous dehydrogenation of 1,4-cyclohexadienes and cyclohexenes to give the corresponding highly-functionalized arenes. Furthermore, various arenes could be efficiently constructed in a one-pot manner via a Diels-Alder reaction and the following dehydrogenation.

Transformation of 1-(1,2-propadienyl)cyclopropanols into substituted hydroquinones employing octacarbonyldicobalt

A novel transformation of 1-(1,2-propadienyl)cyclopropanols into substituted 1,4-hydroquinones has been developed utilizing the interaction of 1,2-propadienes and octacarbonyldicobalt (Co2(CO)8). This reaction was applied to the synthesis of vitamin E and K analogs.

Diels-Alder Reactions of 2-pyrylium Cations of 2H-Pyran-2-one and 2H-1-Benzopyran-2-one Derivatives

The reactions of 6-methyl-2H-pyran-2-one and 2H-1-benzopyran-2-one with the 2-(trialkylsilyl)oxy dienes 6a-d in the presence of tert-butyldimethylsilyl triflate gave the cycloadducts 7a-c and 8a-d regio- and stereoselectively in moderate yields.The ring junction in the cycloadducts is cis.The stereochemistry of 8a-d is discussed in terms of the 1H NMR spectra of the compounds.Similar reactions of 3-(ethoxycarbonyl)-2-pyrones and 3-(alkoxycarbonyl)coumarins with the 2-(trialkylsilyl)oxy dienes 6a-e gave the cycloadducts 14-18 in satisfactory yields.Dehydrogenation of 7c, 8b, and 8c with DDQ in refluxing toluene afforded 23-25, respectively.